Concepedia

Enhancer Spacing

Enhancer Spacing is a genomic architectural feature that refers to the precise physical distance between an enhancer element and its target promoter or other regulatory components, distinguishing it from related enhancer properties by specifying the spatial interval critical for optimal transcriptional regulation.

4

Publications

521

Citations

25

Authors

13

Institutions

Publications per year

2017–2026

1

Parents

Publications

4

Suboptimization of developmental enhancers

Emma K. Farley, K.M. Olson, Wei Zhang et al. · Science · 2015 · 361 citations · Full text

, , +17

Spacing ensures autonomous expression of different stripe enhancers in the <i>even-skipped</i> promoter

Stephen Small, David N. Arnosti, Michael Levine · Development · 1993 · 103 citations

, , +17

Functional Analysis of an Eye Enhancer of the Drosophila eyes absent Gene: Differential Regulation by Eye Specification Genes

Quang T Bui, John E. Zimmerman, Haixi Liu et al. · Developmental Biology · 2000 · 34 citations

, , +17

Systematic analysis of naturally occurring insertions and deletions that alter transcription factor spacing identifies tolerant and sensitive transcription factor pairs

Zeyang Shen, Rick Z. Li, Thomas A Prohaska et al. · eLife · 2022 · 23 citations · Full text

, , +17

1–4 of 4

Authors

25

  1. ML
    Michael Levine

    University of California, Berkeley, United States

    2 publications · 464 citations

    2

    h-index

  2. HL
    Haixi Liu

    University of Pennsylvania, United States

    1 publications · 34 citations

    1

    h-index

  3. DS
    Daniel S. Rokhsar

    University of California, Berkeley, United States

    1 publications · 361 citations

    1

    h-index

  4. CK
    Christopher K. Glass

    University of California San Diego, United States

    1 publications · 23 citations

    1

    h-index

  5. SS
    Stephen Small

    New York University, United States

    1 publications · 103 citations

    1

    h-index

1–5 of 25

Institutions

13

  1. University of California San Diego

    San Diego, United States

    2 h-index

    11 publications

    591 citations

  2. Amsterdam University Medical Centers

    Amsterdam, The Netherlands

    1 h-index

    1 publications

    23 citations

  3. McGill University

    Montreal, Canada

    1 h-index

    1 publications

    23 citations

  4. University of Amsterdam

    Amsterdam, The Netherlands

    1 h-index

    1 publications

    23 citations

  5. Nippon Medical School

    Tokyo, Japan

    1 h-index

    1 publications

    23 citations

  6. Princeton University

    Princeton, United States

    1 h-index

    3 publications

    1.1K citations

  7. Innovative Genomics Institute

    Berkeley, United States

    1 h-index

    4 publications

    1.4K citations

  8. Institut thématique Génétique, génomique et bioinformatique

    Paris, France

    1 h-index

    4 publications

    1.4K citations

1–8 of 13

Venues

  1. Development

    1 publications · 103 citations

    1

    h-index

  2. Science

    1 publications · 361 citations

    1

    h-index

  3. Developmental Biology

    1 publications · 34 citations

    1

    h-index

  4. eLife

    1 publications · 23 citations

    1

    h-index

1–4