Concepedia

Enhancer Silencing

Enhancer Silencing is a regulatory mechanism in molecular genetics whereby specific genomic elements suppress the transcriptional activation potential of enhancers, thereby preventing their interaction with target promoters to modulate gene expression.

175

Publications

13.7K

Citations

1.3K

Authors

395

Institutions

Publications per year

2017–2026

50

Parents

Publications

175

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.

Richard Eckner, Mark E. Ewen, David Newsome et al. · Genes & Development · 1994 · 1.1K citations · Full text

, , +13

Phenotypic robustness conferred by apparently redundant transcriptional enhancers

Nicolás Frankel, Gregory K. Davis, Diego Vargas et al. · Nature · 2010 · 547 citations · Full text

, , +12

Targeting neural circuitry in zebrafish using GAL4 enhancer trapping

Ethan K. Scott, Lindsay Mason, Aristides B. Arrenberg et al. · Nature Methods · 2007 · 409 citations

, , +14

Position-effect protection and enhancer blocking by the chicken β-globin insulator are separable activities

Félix Recillas‐Targa, Michael J. Pikaart, Bonnie Burgess-Beusse et al. · Proceedings of the National Academy of Sciences · 2002 · 380 citations

, , +16

SMARCB1 is required for widespread BAF complex–mediated activation of enhancers and bivalent promoters

Robert Nakayama, John L. Pulice, Alfredo M. Valencia et al. · Nature Genetics · 2017 · 296 citations · Full text

, , +13

1–5 of 175

Authors

1.3K

  1. MG
    Mark Groudine

    Fred Hutch Cancer Center, United States

    4 publications · 695 citations

    4

    h-index

  2. EN
    Eric N. Olson

    The University of Texas Southwestern Medical Center, United States

    3 publications · 395 citations

    3

    h-index

  3. TL
    Tiantian Liu

    Washington University in St. Louis, United States

    3 publications · 397 citations

    3

    h-index

  4. XH
    Xiao Huang

    Washington University in St. Louis, United States

    3 publications · 397 citations

    3

    h-index

  5. KM
    Kenneth M. Murphy

    Washington University in St. Louis, United States

    3 publications · 397 citations

    3

    h-index

1–5 of 1.3K

Institutions

395

  1. Harvard University

    Cambridge, United States

    14 h-index

    80 publications

    7.2K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    35 publications

    5.3K citations

  3. National Institutes of Health

    Bethesda, United States

    8 h-index

    26 publications

    5.5K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    26 publications

    777 citations

  5. Broad Institute

    Cambridge, United States

    6 h-index

    34 publications

    2.6K citations

  6. University of California, San Francisco

    San Francisco, United States

    6 h-index

    21 publications

    3.6K citations

  7. University of California San Diego

    San Diego, United States

    6 h-index

    30 publications

    4.4K citations

  8. Brigham and Women's Hospital

    Boston, United States

    5 h-index

    18 publications

    1.3K citations

1–8 of 395

Venues

  1. Molecular and Cellular Biology

    MCB · 17 publications · 1.2K citations

    16

    h-index

  2. Journal of Biological Chemistry

    JBC · 9 publications · 523 citations

    9

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 1K citations

    8

    h-index

  4. Nucleic Acids Research

    8 publications · 424 citations

    8

    h-index

  5. The EMBO Journal

    7 publications · 689 citations

    7

    h-index

1–5