Concepedia

End Bridging Complexes

End Bridging Complexes is a molecular machinery that functions as a structural scaffold in double-strand break repair by mediating the physical association of broken DNA ends through specific protein-protein and protein-DNA interactions to facilitate accurate rejoining.

23

Publications

2.3K

Citations

116

Authors

46

Institutions

Publications per year

2017–2026

5

Parents

Publications

23

Human Rad50/Mre11 Is a Flexible Complex that Can Tether DNA Ends

Martijn de Jager, John van Noort, Dik C. van Gent et al. · Molecular Cell · 2001 · 506 citations · Full text

, , +9

Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

R. Scott Williams, Gabriel Moncalián, Jessica S. Williams et al. · Cell · 2008 · 481 citations · Full text

, , +14

Mycobacterial Ku and Ligase Proteins Constitute a Two-Component NHEJ Repair Machine

Marina Della, Phillip L. Palmbos, Hui-Min Tseng et al. · Science · 2004 · 216 citations · Full text

, , +17

A mechanistic basis for Mre11-directed DNA joining at microhomologies

Tanya T. Paull, Martin Gellert · Proceedings of the National Academy of Sciences · 2000 · 189 citations

, , +16

Geometric and electronic structure of oxyhemocyanin: spectral and chemical correlations to met apo, half met, met, and dimer active sites.

Nancy C. Eickman, Richard S. Himmelwright, Edward I. Solomon · Proceedings of the National Academy of Sciences · 1979 · 99 citations · Full text

, , +17

1–5 of 23

Authors

116

  1. AE
    Alan E. Tomkinson

    University of Maryland, Baltimore, United States

    2 publications · 273 citations

    2

    h-index

  2. CW
    Claire Wyman

    Erasmus MC, Netherlands

    2 publications · 569 citations

    2

    h-index

  3. RK
    Roland Kanaar

    Erasmus MC, Netherlands

    2 publications · 569 citations

    2

    h-index

  4. HT
    Hui-Min Tseng

    University of Maryland, Baltimore, United States

    1 publications · 57 citations

    1

    h-index

  5. HS
    Humberto Sánchez

    Erasmus MC, Netherlands

    1 publications · 63 citations

    1

    h-index

1–5 of 116

Institutions

46

  1. University of Maryland, Baltimore

    Baltimore, United States

    3 h-index

    13 publications

    3.2K citations

  2. Xiamen University

    Xiamen, China

    2 h-index

    5 publications

    128 citations

  3. Center for Systems Biology

    Boston, United States

    1 h-index

    1 publications

    68 citations

  4. Collaborative Innovation Center of Chemistry for Energy Materials

    Shanghai, China

    1 h-index

    1 publications

    40 citations

  5. University of Calgary

    Calgary, Canada

    1 h-index

    2 publications

    136 citations

  6. Northwestern University

    Evanston, United States

    1 h-index

    2 publications

    56 citations

  7. University of Maryland, College Park

    College Park, United States

    1 h-index

    4 publications

    332 citations

  8. University of Southern California

    Los Angeles, United States

    1 h-index

    3 publications

    138 citations

1–8 of 46

Venues

  1. Nucleic Acids Research

    4 publications · 192 citations

    4

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 318 citations

    3

    h-index

  3. 3

    h-index

  4. Chemistry - A European Journal

    2 publications · 50 citations

    2

    h-index

  5. Journal of the American Chemical Society

    JACS · 2 publications · 125 citations

    2

    h-index

1–5