Concepedia

Efflux Transporter Modulation

Efflux Transporter Modulation is a pharmacological strategy that belongs to the class of mucosal permeation enhancement techniques, specifically involving the targeted alteration of efflux transporter activity at epithelial barriers to increase the absorption of substrates by inhibiting or downregulating membrane efflux pumps such as P-glycoprotein.

174

Publications

8K

Citations

913

Authors

350

Institutions

Publications per year

2017–2026

37

Parents

Publications

174

The Effect of Rifampin Treatment on Intestinal Expression of Human MRP Transporters

Martin F. Fromm, Hans-Martin Kauffmann, Péter Fritz et al. · American Journal Of Pathology · 2000 · 278 citations

, , +14

The use of a dendrimer-propranolol prodrug to bypass efflux transporters and enhance oral bioavailability

Antony D’Emanuele, Rachaneekorn Jevprasesphant, Jeffrey Penny et al. · Journal of Controlled Release · 2004 · 265 citations

, , +16

Vitamin E TPGS P-Glycoprotein Inhibition Mechanism: Influence on Conformational Flexibility, Intracellular ATP Levels, and Role of Time and Site of Access

Eva-Maria Collnot, Christiane Baldes, Ulrich F. Schaefer et al. · Molecular Pharmaceutics · 2010 · 217 citations

, , +13

Influence of vitamin E TPGS poly(ethylene glycol) chain length on apical efflux transporters in Caco-2 cell monolayers

Eva-Maria Collnot, Christiane Baldes, Michael F. Wempe et al. · Journal of Controlled Release · 2006 · 185 citations

, , +13

Regulation of ABCG2 Expression at the 3′ Untranslated Region of Its mRNA through Modulation of Transcript Stability and Protein Translation by a Putative MicroRNA in the S1 Colon Cancer Cell Line

Kenneth K.W. To, Zhirong Zhan, Thomas Litman et al. · Molecular and Cellular Biology · 2008 · 163 citations · Full text

, , +17

1–5 of 174

Authors

913

  1. AB
    Andreas Bernkop‐Schnürch

    Universität Innsbruck, Austria

    4 publications · 103 citations

    4

    h-index

  2. RF
    Robert Farinotti

    Hôpital Bichat-Claude-Bernard, France

    4 publications · 136 citations

    4

    h-index

  3. SL
    Susan L. Mercer

    Lipscomb University, United States

    3 publications · 41 citations

    3

    h-index

  4. NY
    Naoki Yamaji

    Okayama University, Japan

    3 publications · 119 citations

    3

    h-index

  5. ND
    Natalie D. Eddington

    University of Maryland, Baltimore, United States

    3 publications · 41 citations

    3

    h-index

1–5 of 913

Institutions

350

  1. University of Toronto

    Toronto, Canada

    5 h-index

    14 publications

    615 citations

  2. University of British Columbia

    Vancouver, Canada

    4 h-index

    10 publications

    441 citations

  3. Okayama University

    Okayama, Japan

    4 h-index

    16 publications

    698 citations

  4. University of Maryland, Baltimore

    Baltimore, United States

    3 h-index

    12 publications

    171 citations

  5. Universität Greifswald

    Greifswald, Germany

    3 h-index

    18 publications

    2.3K citations

  6. Sun Yat-sen University

    Guangzhou, China

    3 h-index

    12 publications

    324 citations

  7. Universität Innsbruck

    Innsbruck, Austria

    3 h-index

    11 publications

    270 citations

  8. Academy of Scientific and Innovative Research

    Ghaziabad, India

    3 h-index

    13 publications

    399 citations

1–8 of 350

Venues

  1. PubMed

    Repository · 6 publications · 305 citations

    6

    h-index

  2. 6

    h-index

  3. International Journal of Pharmaceutics

    5 publications · 92 citations

    5

    h-index

  4. Molecular Pharmaceutics

    4 publications · 310 citations

    4

    h-index

  5. European Journal of Pharmaceutics and Biopharmaceutics

    EJPB · 4 publications · 222 citations

    4

    h-index

1–5