Concepedia

E1cb Elimination

E1cb Elimination is an elimination reaction mechanism characterized by a stepwise process in which the departure of a leaving group follows the initial formation of a stabilized carbanion intermediate, distinguishing it from other elimination pathways by its carbanion-mediated kinetics and strong dependence on substrate acidity.

58

Publications

1.8K

Citations

181

Authors

58

Institutions

Publications per year

2017–2026

9

Variants

E1cb MechanismUnimolecular Conjugate Base Elimination

Parents

Publications

58

Relationships between E2 and E1cB mechanisms of β-elimination

Rory A. More O‘Ferrall · Journal of the Chemical Society B Physical Organic · 1970 · 250 citations

, , +15

Synthesis of Carbamates from Diethoxycarbonyl Hydrazine Derivatives by E1cB Eliminative Cleavage of the <i>N−N′</i>-Bond Rather than Reduction

Philip Magnus, Negar Garizi, Kimberly A. Seibert et al. · Organic Letters · 2009 · 83 citations

, , +6

Change in Rate-Determining Step in an E1cB Mechanism during Aminolysis of Sulfamate Esters in Acetonitrile

William J. Spillane, Paul McGrath, Chris Brack et al. · The Journal of Organic Chemistry · 2001 · 73 citations

, , +16

A concise first total synthesis of narceine imide

Marc Lamblin, Axel Couture, Éric Deniau et al. · Organic & Biomolecular Chemistry · 2007 · 70 citations

, , +13

Free-Energy Surfaces for Liquid-Phase Reactions and Their Use To Study the Border Between Concerted and Nonconcerted α,β-Elimination Reactions of Esters and Thioesters

Yongho Kim, Jerry R. Mohrig, Donald G. Truhlar · Journal of the American Chemical Society · 2010 · 69 citations

, , +12

1–5 of 58

Authors

181

  1. SA
    Sergio Alunni

    University of Perugia, Italy

    6 publications · 143 citations

    6

    h-index

  2. AT
    Alf Thibblin

    Uppsala University, Sweden

    4 publications · 83 citations

    4

    h-index

  3. RA
    Rory A. More O‘Ferrall

    University College Dublin, Ireland

    3 publications · 274 citations

    3

    h-index

  4. ÉD
    Éric Deniau

    Laboratoire de Chimie Organique, France

    3 publications · 166 citations

    3

    h-index

  5. AC
    Axel Couture

    Laboratoire de Chimie Organique, France

    3 publications · 166 citations

    3

    h-index

1–5 of 181

Institutions

58

  1. University of Perugia

    Perugia, Italy

    4 h-index

    14 publications

    462 citations

  2. Uppsala University

    Uppsala, Sweden

    3 h-index

    6 publications

    118 citations

  3. Korea University

    Seoul, South Korea

    2 h-index

    7 publications

    130 citations

  4. Vrije Universiteit Amsterdam

    Amsterdam, The Netherlands

    2 h-index

    2 publications

    62 citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    9 publications

    445 citations

  6. Laboratoire de Chimie Organique

    Paris, France

    2 h-index

    9 publications

    585 citations

  7. Ollscoil na Gaillimhe – University of Galway

    Galway, Ireland

    2 h-index

    6 publications

    318 citations

  8. Division of Chemistry

    Arlington, United States

    1 h-index

    1 publications

    22 citations

1–8 of 58

Venues

  1. Journal of the American Chemical Society

    JACS · 15 publications · 445 citations

    13

    h-index

  2. The Journal of Organic Chemistry

    JOC · 11 publications · 312 citations

    10

    h-index

  3. 7

    h-index

  4. Organic & Biomolecular Chemistry

    5 publications · 152 citations

    5

    h-index

  5. 3

    h-index

1–5