Concepedia

Drb Sensitivity-inducing Factor

DRB Sensitivity-Inducing Factor is a regulatory protein complex within the broader category of transcription elongation factors that specifically mediates the recruitment of positive transcription elongation factor b (P-TEFb) to RNA polymerase II, thereby modulating transcriptional pausing and elongation in response to the inhibitory effects of 5,6-dichloro-1-β-D-ribofuranosylbenzimidazole (DRB).

25

Publications

3K

Citations

105

Authors

43

Institutions

Publications per year

2017–2026

3

Variants

Dsif

Parents

Publications

25

Flavopiridol Inactivates P-TEFb and Blocks Most RNA Polymerase II Transcription in Vivo

Sheng‐Hao Chao, David H. Price · Journal of Biological Chemistry · 2001 · 638 citations · Full text

, , +14

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program

Nathan Gomes, Glen A. Bjerke, Briardo Llorente et al. · Genes & Development · 2006 · 267 citations · Full text

, , +17

Evidence that Negative Elongation Factor Represses Transcription Elongation through Binding to a DRB Sensitivity-Inducing Factor/RNA Polymerase II Complex and RNA

Yuki Yamaguchi, Naoto Inukai, Takashi Narita et al. · Molecular and Cellular Biology · 2002 · 228 citations · Full text

, , +16

Human Transcription Elongation Factor NELF: Identification of Novel Subunits and Reconstitution of the Functionally Active Complex

Takashi Narita, Yuki Yamaguchi, Keiichi Yano et al. · Molecular and Cellular Biology · 2003 · 227 citations · Full text

, , +17

DSIF and NELF Interact with RNA Polymerase II Elongation Complex and HIV-1 Tat Stimulates P-TEFb-mediated Phosphorylation of RNA Polymerase II and DSIF during Transcription Elongation

Yueh‐Hsin Ping, Tariq M. Rana · Journal of Biological Chemistry · 2001 · 204 citations · Full text

, , +17

1–5 of 25

Authors

105

  1. HH
    Hiroshi Handa

    Tokyo Institute of Technology, Japan

    10 publications · 1.2K citations

    10

    h-index

  2. YY
    Yuki Yamaguchi

    Tokyo Institute of Technology, Japan

    9 publications · 1K citations

    9

    h-index

  3. TW
    Tadashi Wada

    Tokyo Institute of Technology, Japan

    7 publications · 1.1K citations

    7

    h-index

  4. TN
    Takashi Narita

    Tokyo Institute of Technology, Japan

    4 publications · 756 citations

    4

    h-index

  5. NI
    Naoto Inukai

    Tokyo Institute of Technology, Japan

    4 publications · 756 citations

    4

    h-index

1–5 of 105

Institutions

43

  1. Tokyo Institute of Technology

    Tokyo, Japan

    10 h-index

    46 publications

    5.2K citations

  2. Kyowa Kirin (Japan)

    Tokyo, Japan

    3 h-index

    7 publications

    1.2K citations

  3. Weizmann Institute of Science

    Rehovot, Israel

    2 h-index

    5 publications

    181 citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    8 publications

    1.4K citations

  5. Research Institute for Bioscience and Biotechnology

    Kathmandu, Nepal

    2 h-index

    14 publications

    3.2K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    9 publications

    130 citations

  7. Pennsylvania State University

    State College, United States

    2 h-index

    4 publications

    400 citations

  8. The University of Osaka

    Osaka, Japan

    1 h-index

    1 publications

    11 citations

1–8 of 43

Venues

  1. Molecular and Cellular Biology

    MCB · 6 publications · 699 citations

    6

    h-index

  2. Journal of Biological Chemistry

    JBC · 5 publications · 1.1K citations

    5

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 514 citations

    3

    h-index

  4. Genes & Development

    2 publications · 380 citations

    2

    h-index

  5. Nucleic Acids Research

    2 publications · 40 citations

    2

    h-index

1–5