Concepedia

Dose Re-escalation

Dose Re-Escalation is a dose modification strategy in clinical pharmacology involving the systematic adjustment of a therapeutic agent's dosage upward after an initial reduction, aimed at re-establishing efficacy while maintaining tolerability.

95

Publications

5K

Citations

707

Authors

375

Institutions

Publications per year

2017–2026

33

Parents

Publications

95

Dose escalation with 3D conformal treatment: five year outcomes, treatment optimization, and future directions

G. Hanks, Alexandra L. Hanlon, Timothy E. Schultheiss et al. · International Journal of Radiation Oncology*Biology*Physics · 1998 · 423 citations

, , +15

Complications from radiotherapy dose escalation in prostate cancer: preliminary results of a randomized trial

Mark R Storey, Alan Pollack, Gunar K. Zagars et al. · International Journal of Radiation Oncology*Biology*Physics · 2000 · 420 citations

, , +16

Evidence for differential acquired drug resistance to anti-tumour necrosis factor agents in rheumatoid arthritis

Axel Finckh · Annals of the Rheumatic Diseases · 2005 · 177 citations · Full text

, , +13

A phase I evaluation of multitargeted antifolate (MTA, LY231514), administered every 21 days, utilizing the modified continual reassessment method for dose escalation

David Rinaldi, John G. Kuhn, Howard A. Burris et al. · Cancer Chemotherapy and Pharmacology · 1999 · 175 citations

, , +12

Early clinical remission and normalisation of CRP are the strongest predictors of efficacy, mucosal healing and dose escalation during the first year of adalimumab therapy in Crohn’s disease

László Kiss, Tamás Szamosi, Tamás Molnár et al. · Alimentary Pharmacology & Therapeutics · 2011 · 160 citations · Full text

, , +17

1–5 of 95

Authors

707

  1. AI
    Alexia Iasonos

    Memorial Sloan Kettering Cancer Center, United States

    4 publications · 103 citations

    4

    h-index

  2. JO
    John O’Quigley

    Sorbonne Université, France

    4 publications · 169 citations

    4

    h-index

  3. HM
    Hagop M. Kantarjian

    The University of Texas MD Anderson Cancer Center, United States

    3 publications · 363 citations

    3

    h-index

  4. JE
    Jörge E. Cortes

    The University of Texas MD Anderson Cancer Center, United States

    2 publications · 305 citations

    2

    h-index

  5. SB
    Stephanie Brown

    Mount Vernon Cancer Centre, United Kingdom

    2 publications · 66 citations

    2

    h-index

1–5 of 707

Institutions

375

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    9 h-index

    30 publications

    4.7K citations

  2. Memorial Sloan Kettering Cancer Center

    New York, United States

    8 h-index

    16 publications

    592 citations

  3. Inserm

    Paris, France

    5 h-index

    14 publications

    543 citations

  4. Sorbonne Université

    Paris, France

    4 h-index

    10 publications

    366 citations

  5. Princess Margaret Cancer Centre

    Toronto, Canada

    4 h-index

    3 publications

    133 citations

  6. The University of Melbourne

    Melbourne, Australia

    3 h-index

    4 publications

    125 citations

  7. University of Miami

    Coral Gables, United States

    3 h-index

    3 publications

    180 citations

  8. Massachusetts General Hospital

    Boston, United States

    3 h-index

    3 publications

    98 citations

1–8 of 375

Venues

  1. Blood

    9 publications · 533 citations

    9

    h-index

  2. 6

    h-index

  3. Radiotherapy and Oncology

    3 publications · 83 citations

    3

    h-index

  4. European Journal of Cancer

    3 publications · 81 citations

    3

    h-index

  5. Journal of Clinical Oncology

    3 publications · 209 citations

    3

    h-index

1–5