Concepedia

Dose Adjustment Modeling

Dose Adjustment Modeling is a mathematical framework used in pharmacokinetics to systematically modify drug dosage regimens based on patient-specific physiological and pathophysiological factors in order to maintain therapeutic efficacy and minimize toxicity.

167

Publications

5.3K

Citations

890

Authors

384

Institutions

Publications per year

2017–2026

47

Parents

Publications

167

Role of Pharmacokinetics in Drug Dosage Adjustment. I. Pharmacologic Effect Kinetics and Apparent Volume of Distribution of Digoxin

Richard H. Reuning, Richard A. Sams, Robert E. Notari · The Journal of Clinical Pharmacology and New Drugs · 1973 · 149 citations · Full text

, , +9

A probabilistic approach to glucose prediction and insulin dose adjustment: description of metabolic model and pilot evaluation study

Steen Andreassen, Jonathan Benn, Roman Hovorka et al. · Computer Methods and Programs in Biomedicine · 1994 · 136 citations

, , +14

Individualization of phenytoin dosage regimens

Thomas M. Ludden, John P. Allen, William A. Valutsky et al. · Clinical Pharmacology & Therapeutics · 1977 · 107 citations

, , +13

Model-based Dose Selection for Phase III Rivaroxaban Study in Japanese Patients with Non-valvular Atrial Fibrillation

Takahiko Tanigawa, Masato Kaneko, Kensei Hashizume et al. · Drug Metabolism and Pharmacokinetics · 2012 · 106 citations

, , +15

Mathematical modelling of hepatitis C treatment for injecting drug users

Natasha K. Martin, Peter Vickerman, Matthew Hickman · Journal of Theoretical Biology · 2011 · 106 citations · Full text

, , +16

1–5 of 167

Authors

890

  1. PM
    Pierre Marquet

    Université de Limoges, France

    6 publications · 223 citations

    6

    h-index

  2. JW
    Jean‐Baptiste Woillard

    Université de Limoges, France

    5 publications · 200 citations

    5

    h-index

  3. JD
    Jean Debord

    Université de Limoges, France

    5 publications · 208 citations

    5

    h-index

  4. FS
    Franck Saint‐Marcoux

    Université de Limoges, France

    4 publications · 108 citations

    4

    h-index

  5. MS
    Marco Siccardi

    University of Liverpool, United Kingdom

    4 publications · 100 citations

    4

    h-index

1–5 of 890

Institutions

384

  1. Inserm

    Paris, France

    8 h-index

    35 publications

    1.5K citations

  2. Radboud University Nijmegen

    Nijmegen, The Netherlands

    6 h-index

    16 publications

    382 citations

  3. Université de Limoges

    Limoges, France

    6 h-index

    29 publications

    1K citations

  4. University of Liverpool

    Liverpool, United Kingdom

    6 h-index

    21 publications

    558 citations

  5. Centre Hospitalier Universitaire de Limoges

    Limoges, France

    4 h-index

    12 publications

    518 citations

  6. Uppsala University

    Uppsala, Sweden

    4 h-index

    10 publications

    311 citations

  7. Radboud University Medical Center

    Nijmegen, The Netherlands

    4 h-index

    12 publications

    274 citations

  8. University of Chicago

    Chicago, United States

    4 h-index

    20 publications

    1.1K citations

1–8 of 384

Venues

  1. Therapeutic Drug Monitoring

    15 publications · 318 citations

    13

    h-index

  2. British Journal of Clinical Pharmacology

    BJCP · 9 publications · 217 citations

    9

    h-index

  3. Clinical Pharmacokinetics

    8 publications · 188 citations

    8

    h-index

  4. Clinical Pharmacology & Therapeutics

    CPT · 8 publications · 432 citations

    7

    h-index

  5. PubMed

    Repository · 6 publications · 129 citations

    6

    h-index

1–5