Concepedia

Dosage Balance

Dosage Balance is a theoretical construct in genomics that explains the selective pressure to maintain stoichiometric equilibrium among interacting gene products following genome duplication, distinguishing it from other genomic balance hypotheses by emphasizing the dosage sensitivity of molecular complexes and regulatory networks.

46

Publications

4.8K

Citations

194

Authors

112

Institutions

Publications per year

2017–2026

12

Parents

Publications

46

Landscape of X chromosome inactivation across human tissues

Taru Tukiainen, Alexandra–Chloé Villani, Angela Yen et al. · Nature · 2017 · 1.2K citations · Full text

, , +14

Homoeologous shuffling and chromosome compensation maintain genome balance in resynthesized allopolyploid <i>Brassica napus</i>

Zhiyong Xiong, Robert T. Gaeta, J. Chris Pires · Proceedings of the National Academy of Sciences · 2011 · 451 citations · Full text

, , +14

Ohnologs in the human genome are dosage balanced and frequently associated with disease

Takashi Makino, Aoife McLysaght · Proceedings of the National Academy of Sciences · 2010 · 292 citations · Full text

, , +17

The multiple fates of gene duplications: Deletion, hypofunctionalization, subfunctionalization, neofunctionalization, dosage balance constraints, and neutral variation

James A. Birchler, Hua Yang · The Plant Cell · 2022 · 286 citations · Full text

, , +17

Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammals

Xun Lan, Jonathan K. Pritchard · Science · 2016 · 220 citations · Full text

, , +14

1–5 of 46

Authors

194

  1. LC
    Lorenzo Carretero‐Paulet

    Universitat de Barcelona, Spain

    3 publications · 203 citations

    3

    h-index

  2. YV
    Yves Van de Peer

    Ghent University, Belgium

    3 publications · 203 citations

    3

    h-index

  3. AF
    Ariel Fernández

    University of Chicago, United States

    3 publications · 87 citations

    3

    h-index

  4. AT
    A Teufel

    University of Wyoming, United States

    3 publications · 151 citations

    3

    h-index

  5. DG
    Daniel G. MacArthur

    Broad Institute, United States

    2 publications · 1.3K citations

    2

    h-index

1–5 of 194

Institutions

112

  1. University of Missouri

    Columbia, United States

    4 h-index

    7 publications

    2K citations

  2. Massachusetts General Hospital

    Boston, United States

    3 h-index

    31 publications

    16.2K citations

  3. Harvard University

    Cambridge, United States

    3 h-index

    15 publications

    6.8K citations

  4. Stanford University

    Stanford, United States

    3 h-index

    4 publications

    1.7K citations

  5. University of Georgia

    Athens, United States

    3 h-index

    4 publications

    1K citations

  6. VIB-UGent Center for Plant Systems Biology

    Ghent, Belgium

    3 h-index

    12 publications

    918 citations

  7. Ghent University

    Ghent, Belgium

    3 h-index

    12 publications

    918 citations

  8. University of Pretoria

    Pretoria, South Africa

    3 h-index

    3 publications

    203 citations

1–8 of 112

Venues

  1. Molecular Biology and Evolution

    MBE · 6 publications · 269 citations

    6

    h-index

  2. PLoS Genetics

    3 publications · 133 citations

    3

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 942 citations

    3

    h-index

  4. PubMed

    Repository · 3 publications · 152 citations

    3

    h-index

  5. The Plant Cell

    4 publications · 462 citations

    3

    h-index

1–5