Concepedia

Dorsal Morphogen Gradient

Dorsal Morphogen Gradient is a concentration gradient of the Dorsal transcription factor protein along the dorsal-ventral axis of the Drosophila embryo that functions as a morphogen to differentially regulate target gene expression in a concentration-dependent manner, thereby specifying distinct cell fates during early development.

50

Publications

5.5K

Citations

160

Authors

60

Institutions

Publications per year

2017–2026

4

Parents

Publications

50

A molecular gradient in early Drosophila embryos and its role in specifying the body pattern

Paul M. Macdonald, Gary Struhl · Nature · 1986 · 497 citations

, , +16

The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila

Christine A. Rushlow, Kyuhyung Han, James L. Manley et al. · Cell · 1989 · 483 citations · Full text

, , +13

The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos.

Jin Jiang, Dave Kosman, Y. Tony Ip et al. · Genes & Development · 1991 · 364 citations · Full text

, , +17

Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen

Jie Jiang · Cell · 1993 · 328 citations · Full text

, , +16

The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo.

Y. Tony Ip, R E Park, Dave Kosman et al. · Genes & Development · 1992 · 327 citations · Full text

, , +16

1–5 of 50

Authors

160

  1. ML
    Michael Levine

    University of California, Berkeley, United States

    7 publications · 1.6K citations

    7

    h-index

  2. YK
    Yoosik Kim

    Korea Advanced Institute of Science and Technology, South Korea

    3 publications · 168 citations

    3

    h-index

  3. GT
    Gregory T. Reeves

    North Carolina State University, United States

    3 publications · 163 citations

    3

    h-index

  4. YT
    Y. Tony Ip

    University of Massachusetts Chan Medical School, United States

    3 publications · 1K citations

    3

    h-index

  5. SY
    Stanislav Y. Shvartsman

    Princeton University, United States

    3 publications · 168 citations

    3

    h-index

1–5 of 160

Institutions

60

  1. Princeton University

    Princeton, United States

    6 h-index

    20 publications

    1.4K citations

  2. University of California San Diego

    San Diego, United States

    4 h-index

    13 publications

    3.6K citations

  3. University of California, Berkeley

    Berkeley, United States

    4 h-index

    10 publications

    731 citations

  4. North Carolina State University

    Raleigh, United States

    4 h-index

    10 publications

    394 citations

  5. Columbia University

    New York, United States

    4 h-index

    11 publications

    4.1K citations

  6. University of California, Los Angeles

    Los Angeles, United States

    3 h-index

    13 publications

    1.2K citations

  7. Yeshiva University

    New York, United States

    2 h-index

    3 publications

    420 citations

  8. Case Western Reserve University

    Cleveland, United States

    2 h-index

    8 publications

    167 citations

1–8 of 60

Venues

  1. Development

    10 publications · 511 citations

    10

    h-index

  2. Genes & Development

    9 publications · 1.8K citations

    9

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 5 publications · 424 citations

    5

    h-index

  4. Developmental Biology

    4 publications · 275 citations

    4

    h-index

  5. PLoS Computational Biology

    3 publications · 64 citations

    3

    h-index

1–5