Concepedia

Donor Template Design

Donor Template Design is a methodological framework in gene editing that specifies the construction and sequence composition of exogenous DNA molecules to enable precise integration into target genomic loci via homology-directed repair.

14

Publications

1.1K

Citations

85

Authors

29

Institutions

Publications per year

2017–2026

10

Parents

Publications

14

CRISPR‐Cas9 Genome Editing in <i>Drosophila</i>

Scott J. Gratz, C. Dustin Rubinstein, Melissa M. Harrison et al. · Current Protocols in Molecular Biology · 2015 · 242 citations · Full text

, , +16

Efficient modification of <i>CCR5</i> in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template

Blythe Sather, Guillermo S. Romano Ibarra, Karen Sommer et al. · Science Translational Medicine · 2015 · 229 citations · Full text

, , +9

Optimizing the DNA Donor Template for Homology-Directed Repair of Double-Strand Breaks

Fei Song, Knut Stieger · Molecular Therapy — Nucleic Acids · 2017 · 141 citations · Full text

, , +14

Optimized design parameters for CRISPR Cas9 and Cas12a homology-directed repair

Mollie S. Schubert, Bernice Thommandru, Jessica Woodley et al. · Scientific Reports · 2021 · 117 citations · Full text

, , +17

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination

Oguz Kanca, Jonathan Zirin, Yanhui Hu et al. · eLife · 2022 · 89 citations · Full text

, , +17

1–5 of 14

Authors

85

  1. DJ
    David J. Rawlings

    University of Washington, United States

    2 publications · 251 citations

    2

    h-index

  2. BS
    Blythe Sather

    University of Washington, United States

    1 publications · 229 citations

    1

    h-index

  3. TA
    Thor A. Wagner

    University of Washington, United States

    1 publications · 229 citations

    1

    h-index

  4. ZZ
    Zhongyuan Zuo

    Baylor College of Medicine, United States

    1 publications · 89 citations

    1

    h-index

  5. HJ
    Hugo J. Bellen

    Baylor College of Medicine, United States

    1 publications · 89 citations

    1

    h-index

1–5 of 85

Institutions

29

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    4 publications

    293 citations

  2. University of Washington

    Seattle, United States

    2 h-index

    4 publications

    709 citations

  3. Baylor College of Medicine

    Houston, United States

    1 h-index

    8 publications

    712 citations

  4. Seattle University

    Seattle, United States

    1 h-index

    1 publications

    22 citations

  5. Nanjing General Hospital of Nanjing Military Command

    Nanjing, China

    1 h-index

    1 publications

    23 citations

  6. Virginia Mason Medical Center

    Seattle, United States

    1 h-index

    3 publications

    66 citations

  7. BGI Group (China)

    Shenzhen, China

    1 h-index

    1 publications

    117 citations

  8. Integrated DNA Technologies (United States)

    Coralville, United States

    1 h-index

    8 publications

    936 citations

1–8 of 29

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 1 publications · 68 citations

    1

    h-index

  2. Current Protocols in Molecular Biology

    1 publications · 242 citations

    1

    h-index

  3. Molecular Therapy — Nucleic Acids

    1 publications · 141 citations

    1

    h-index

  4. Frontiers in Cell and Developmental Biology

    1 publications · 47 citations

    1

    h-index

  5. Molecular Therapy

    1 publications · 22 citations

    1

    h-index

1–5