Concepedia

Dna End Recognition

DNA End Recognition is a molecular mechanism within the non-homologous end joining pathway that specifically identifies and binds to double-strand break sites in DNA, distinguishing itself from other DNA repair recognition processes by its independence from sequence homology and its reliance on the Ku70/Ku80 heterodimer to initiate repair.

167

Publications

14.8K

Citations

708

Authors

250

Institutions

Publications per year

2017–2026

24

Parents

Publications

167

The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen

Tanya Gottlieb, Stephen P. Jackson · Cell · 1993 · 1.2K citations

, , +14

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways

Minli Wang, Wei‐Zhong Wu, Wenqi Wu et al. · Nucleic Acids Research · 2006 · 800 citations · Full text

, , +17

A Critical Role for DNA End-Joining Proteins in Both Lymphogenesis and Neurogenesis

Yijie Gao, Sun Yi, Karen M. Frank et al. · Cell · 1998 · 680 citations · Full text

, , +15

Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

R. Scott Williams, Gabriel Moncalián, Jessica S. Williams et al. · Cell · 2008 · 481 citations · Full text

, , +14

Synapsis of DNA ends by DNA‐dependent protein kinase

Lisa G. DeFazio · The EMBO Journal · 2002 · 351 citations · Full text

, , +7

1–5 of 167

Authors

708

  1. AE
    Alan E. Tomkinson

    University of Maryland, Baltimore, United States

    5 publications · 518 citations

    5

    h-index

  2. PC
    Patrick Calsou

    Centre National de la Recherche Scientifique, France

    5 publications · 419 citations

    5

    h-index

  3. SP
    Stephen P. Jackson

    The Gurdon Institute, United Kingdom

    4 publications · 1.6K citations

    4

    h-index

  4. AG
    Anne Grove

    Louisiana State University, United States

    4 publications · 78 citations

    4

    h-index

  5. JA
    John A. Tainer

    Scripps Research Institute, United States

    4 publications · 1.2K citations

    4

    h-index

1–5 of 708

Institutions

250

  1. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    62 publications

    2.9K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    11 h-index

    34 publications

    10.8K citations

  3. National Institutes of Health

    Bethesda, United States

    11 h-index

    42 publications

    2.8K citations

  4. Stanford University

    Stanford, United States

    7 h-index

    17 publications

    3.2K citations

  5. National Institute of Diabetes and Digestive and Kidney Diseases

    Bethesda, United States

    6 h-index

    21 publications

    973 citations

  6. The University of Texas at San Antonio Health Science Center

    San Antonio, United States

    6 h-index

    22 publications

    3.5K citations

  7. University of Sussex

    Brighton, United Kingdom

    5 h-index

    26 publications

    3.1K citations

  8. Harvard University

    Cambridge, United States

    5 h-index

    20 publications

    2K citations

1–8 of 250

Venues

  1. Journal of Biological Chemistry

    JBC · 31 publications · 2.7K citations

    25

    h-index

  2. Nucleic Acids Research

    24 publications · 1.6K citations

    18

    h-index

  3. Journal of Molecular Biology

    JMB · 13 publications · 999 citations

    13

    h-index

  4. The EMBO Journal

    9 publications · 1.1K citations

    9

    h-index

  5. Molecular Cell

    8 publications · 722 citations

    8

    h-index

1–5