Concepedia

Dna Binding Cleft

The "DNA Binding Cleft" is a structural compartment within RNA polymerase that serves as the primary site for duplex DNA interaction, distinguished by its role in accommodating and guiding the template and non-template DNA strands during transcription initiation and elongation.

273

Publications

26.3K

Citations

1.3K

Authors

396

Institutions

Publications per year

2017–2026

33

Parents

Publications

273

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

Cornelis Murre, Patrick Page-McCaw, David Baltimore · Cell · 1989 · 2.7K citations

, , +16

Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor

Lori A. Kohlstaedt, J Wang, Jonathan M. Friedman et al. · Science · 1992 · 1.9K citations

, , +17

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

James T. Kadonaga, Kristin Carner, Frank R. Masiarz et al. · Cell · 1987 · 1.6K citations

, , +16

Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution

Averell Gnatt, Patrick Cramer, Jianhua Fu et al. · Science · 2001 · 903 citations · Full text

, , +17

Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA

Takashi Yamano, Hiroshi Nishimasu, Bernd Zetsche et al. · Cell · 2016 · 782 citations · Full text

, , +15

1–5 of 273

Authors

1.3K

  1. TA
    Thomas A. Steitz

    Yale University, United States

    5 publications · 1.1K citations

    5

    h-index

  2. PC
    Patrick Cramer

    Max Planck Institute for Biophysical Chemistry, Germany

    4 publications · 1.1K citations

    4

    h-index

  3. KO
    Kazuhiro Ogata

    Yokohama City University, Japan

    3 publications · 124 citations

    3

    h-index

  4. MB
    Martin Buck

    Imperial College London, United Kingdom

    3 publications · 104 citations

    3

    h-index

  5. ME
    Mair E. A. Churchill

    University of Colorado Denver, United States

    3 publications · 194 citations

    3

    h-index

1–5 of 1.3K

Institutions

396

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    14 h-index

    31 publications

    19.5K citations

  2. National Institutes of Health

    Bethesda, United States

    12 h-index

    56 publications

    5.8K citations

  3. Harvard University

    Cambridge, United States

    9 h-index

    26 publications

    2.3K citations

  4. Rutgers, The State University of New Jersey

    New Brunswick, United States

    8 h-index

    19 publications

    1.4K citations

  5. University of California, Berkeley

    Berkeley, United States

    6 h-index

    20 publications

    4.5K citations

  6. Lawrence Berkeley National Laboratory

    Berkeley, United States

    5 h-index

    13 publications

    2.3K citations

  7. Stanford University

    Stanford, United States

    5 h-index

    17 publications

    5.6K citations

  8. National Cancer Institute

    Bethesda, United States

    5 h-index

    13 publications

    921 citations

1–8 of 396

Venues

  1. Journal of Molecular Biology

    JMB · 34 publications · 1.6K citations

    24

    h-index

  2. Journal of Biological Chemistry

    JBC · 18 publications · 950 citations

    15

    h-index

  3. Nucleic Acids Research

    14 publications · 513 citations

    14

    h-index

  4. The EMBO Journal

    12 publications · 1.2K citations

    12

    h-index

  5. Biochemistry

    9 publications · 324 citations

    9

    h-index

1–5