Concepedia

Diversity-generating Recombination

Diversity-Generating Recombination is a genetic mechanism in the adaptive immune system that belongs to the class of site-specific recombination processes, distinguished by its targeted rearrangement of variable (V), diversity (D), and joining (J) gene segments in lymphocyte precursor cells to generate a vast repertoire of antigen receptor specificities.

19

Publications

1.4K

Citations

74

Authors

38

Institutions

Publications per year

2017–2026

2

Variants

V(d)j Recombination

Parents

Publications

19

Mice Lacking TdT: Mature Animals with an Immature Lymphocyte Repertoire

Susan Gilfillan, Andrée Dierich, Marianne LeMeur et al. · Science · 1993 · 450 citations

, , +17

Var gene diversity in Plasmodium falciparum is generated by frequent recombination events

Helen Taylor, S Kyes, Chris Newbold · Molecular and Biochemical Parasitology · 2000 · 148 citations

, , +14

An evolutionary approach with diversity guarantee and well-informed grouping recombination for graph coloring

Daniel Cosmin Porumbel, Jin‐Kao Hao, Pascale Kuntz · Computers & Operations Research · 2010 · 102 citations

, , +10

<i>mgp</i>B and <i>mgp</i>C sequence diversity in <i>Mycoplasma genitalium</i> is generated by segmental reciprocal recombination with repetitive chromosomal sequences

Stefanie L. Iverson‐Cabral, Sabina G. Astete, Craig R. Cohen et al. · Molecular Microbiology · 2007 · 82 citations · Full text

, , +11

Evidence that Immunoglobulin V<sub>H</sub>-DJ Recombination Does Not Require Germ Line Transcription of the Recombining Variable Gene Segment

Cristina Angelin‐Duclos, Kathryn Calame · Molecular and Cellular Biology · 1998 · 77 citations · Full text

, , +17

1–5 of 19

Authors

74

  1. PA
    Patricia A. Totten

    University of Washington, United States

    2 publications · 103 citations

    2

    h-index

  2. GC
    George Chaconas

    University of Calgary, Canada

    2 publications · 54 citations

    2

    h-index

  3. MF
    Matthias Frank

    University of Tübingen, Germany

    1 publications · 76 citations

    1

    h-index

  4. AD
    Anqi Deng

    Center for Excellence in Molecular Cell Science, China

    1 publications · 39 citations

    1

    h-index

  5. TB
    T. Baltz

    Université de Bordeaux, France

    1 publications · 65 citations

    1

    h-index

1–5 of 74

Institutions

38

  1. University of Washington

    Seattle, United States

    2 h-index

    2 publications

    103 citations

  2. University of Calgary

    Calgary, Canada

    2 h-index

    2 publications

    54 citations

  3. German Primate Center

    Göttingen, Germany

    1 h-index

    1 publications

    10 citations

  4. Universitat Pompeu Fabra

    Barcelona, Spain

    1 h-index

    1 publications

    10 citations

  5. Ontario Genomics

    Toronto, Canada

    1 h-index

    1 publications

    41 citations

  6. Columbia University

    New York, United States

    1 h-index

    1 publications

    77 citations

  7. Center for Excellence in Molecular Cell Science

    Shanghai, China

    1 h-index

    1 publications

    39 citations

  8. Sun Yat-sen University

    Guangzhou, China

    1 h-index

    1 publications

    39 citations

1–8 of 38

Venues

  1. Molecular Microbiology

    3 publications · 121 citations

    3

    h-index

  2. Genes & Development

    1 publications · 65 citations

    1

    h-index

  3. Science

    1 publications · 450 citations

    1

    h-index

  4. Retrovirology

    1 publications · 10 citations

    1

    h-index

  5. International Journal for Parasitology

    1 publications · 76 citations

    1

    h-index

1–5