Concepedia

Concept

disease heterogeneity

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343

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33.5K

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2.8K

Authors

876

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About

Disease heterogeneity is the phenomenon characterized by significant variations in clinical presentation, underlying biological mechanisms, pathological features, progression patterns, and responses to treatment among individuals diagnosed with the same disease entity. As a fundamental research concept, it involves the systematic investigation and classification of these diverse manifestations and etiologies to identify distinct subtypes, endotypes, or subgroups within a broadly defined disease category. Understanding disease heterogeneity is crucial for advancing precision medicine, improving diagnostic accuracy, predicting prognosis, and developing targeted therapeutic strategies optimized for specific patient populations or even individual patients.

Top Authors

Rankings shown are based on concept H-Index.

JH

University College London

AG

Washington University in St. Louis

CV

University of Antwerp

MN

University College London

RB

Dana-Farber Cancer Institute

Top Institutions

Rankings shown are based on concept H-Index.

University College London

London, United Kingdom

Karolinska Institutet

Stockholm, Sweden

Harvard University

Cambridge, United States

University of Washington

Seattle, United States

National Institutes of Health

Bethesda, United States

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