Concepedia

Dgcr8-mediated Processing

DGCR8-Mediated Processing is a molecular biogenesis mechanism in which the DGCR8 protein, as part of the microprocessor complex, selectively recognizes and cleaves primary microRNA transcripts into precursor microRNAs during the initial nuclear phase of microRNA maturation.

92

Publications

13.1K

Citations

657

Authors

221

Institutions

Publications per year

2017–2026

25

Parents

Publications

92

The Drosha-DGCR8 complex in primary microRNA processing

Jinju Han, Yoontae Lee, Kyu-Hyun Yeom et al. · Genes & Development · 2004 · 2.2K citations · Full text

, , +17

Molecular Basis for the Recognition of Primary microRNAs by the Drosha-DGCR8 Complex

Jinju Han, Yoontae Lee, Kyu‐Hyeon Yeom et al. · Cell · 2006 · 1.5K citations · Full text

, , +13

DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal

Yangming Wang, Rostislav Medvid, Collin Melton et al. · Nature Genetics · 2007 · 1K citations · Full text

, , +14

METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N 6‐methyladenosine‐dependent primary MicroRNA processing

Jinzhao Ma, Fu Yang, Chuanchuan Zhou et al. · Hepatology · 2016 · 999 citations

, , +17

Posttranscriptional Crossregulation between Drosha and DGCR8

Jinju Han, Jakob Skou Pedersen, Cassandra D. Belair et al. · Cell · 2009 · 445 citations · Full text

, , +5

1–5 of 92

Authors

657

  1. FG
    Feng Guo

    University of California, Los Angeles, United States

    6 publications · 273 citations

    6

    h-index

  2. RS
    Rachel Senturia

    University of California, Los Angeles, United States

    5 publications · 259 citations

    5

    h-index

  3. RB
    Robert Blelloch

    University of California, San Francisco, United States

    4 publications · 1.5K citations

    4

    h-index

  4. JH
    Jinju Han

    Seoul National University, South Korea

    4 publications · 4.5K citations

    4

    h-index

  5. RC
    Ran Chen

    Chinese Academy of Sciences, China

    4 publications · 160 citations

    4

    h-index

1–5 of 657

Institutions

221

  1. University of California, Los Angeles

    Los Angeles, United States

    8 h-index

    40 publications

    2.2K citations

  2. Seoul National University

    Seoul, South Korea

    7 h-index

    38 publications

    30.1K citations

  3. University of California, San Francisco

    San Francisco, United States

    5 h-index

    16 publications

    5.3K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    19 publications

    2.8K citations

  5. State Key Laboratory of Oncogene and Related Genes

    Shanghai, China

    3 h-index

    3 publications

    104 citations

  6. Ardabil University of Medical Sciences

    Ardabil, Iran

    3 h-index

    9 publications

    231 citations

  7. Baylor College of Medicine

    Houston, United States

    3 h-index

    5 publications

    668 citations

  8. Heidelberg University

    Heidelberg, Germany

    3 h-index

    15 publications

    2.5K citations

1–8 of 221

Venues

  1. Nucleic Acids Research

    9 publications · 842 citations

    9

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 755 citations

    6

    h-index

  3. RNA

    5 publications · 296 citations

    5

    h-index

  4. Nature Communications

    4 publications · 325 citations

    4

    h-index

  5. Journal of Biological Chemistry

    JBC · 4 publications · 190 citations

    4

    h-index

1–5