Concepedia

Derived Minimal Effect Levels

Derived Minimal Effect Levels is a toxicological threshold value representing the lowest exposure level at which a statistically significant adverse effect is observed in a studied population, derived from experimental or epidemiological data to inform the establishment of safe exposure limits.

6

Publications

137

Citations

37

Authors

14

Institutions

Publications per year

2017–2026

1

Variants

Dmel

Parents

Publications

6

Health effects classification and its role in the derivation of minimal risk levels: Immunological effects

Henry Abadin, Chu-Yang Chou, Fernando Llados · Regulatory Toxicology and Pharmacology · 2006 · 37 citations

, , +10

Antibiotics in the human food chain: Establishing no effect levels of tetracycline, neomycin, and erythromycin using a chemostat model of the human colonic microflora

Robert J. Carman, Mary Alice Simon, H. Earl Petzold et al. · Regulatory Toxicology and Pharmacology · 2005 · 35 citations

, , +15

Interpreting REACH guidance in the determination of the derived no effect level (DNEL)

Marisa L. Kreider, E. S. Williams · Regulatory Toxicology and Pharmacology · 2010 · 19 citations

, , +5

Integrated Pharmacokinetic/Pharmacodynamic Analysis for Determining the Minimal Anticipated Biological Effect Level of a Novel Anti-CD28 Receptor Antagonist BMS-931699

Zheng Yang, Haiqing Wang, Theodora W. Salcedo et al. · Journal of Pharmacology and Experimental Therapeutics · 2015 · 19 citations

, , +17

A quantitative risk assessment for skin sensitizing plant protection products: Linking derived No-Effect levels (DNELs) with agricultural exposure models

Olivier Sanvido, Kaspar Schmid, Rex FitzGerald et al. · Regulatory Toxicology and Pharmacology · 2018 · 17 citations · Full text

, , +16

1–5 of 6

Authors

37

  1. HE
    Heraline E. Hicks

    Agency for Toxic Substances and Disease Registry, United States

    1 publications · 10 citations

    1

    h-index

  2. CC
    Chu-Yang Chou

    Agency for Toxic Substances and Disease Registry, United States

    1 publications · 37 citations

    1

    h-index

  3. NB
    Nancy B. Hopf

    University of Lausanne, Switzerland

    1 publications · 17 citations

    1

    h-index

  4. LA
    Lumelle A. Schneeweis

    Bristol-Myers Squibb (United States), United States

    1 publications · 19 citations

    1

    h-index

  5. AD
    A. David Rodrigues

    Pfizer (United States), United States

    1 publications · 19 citations

    1

    h-index

1–5 of 37

Institutions

14

  1. Agency for Toxic Substances and Disease Registry

    Atlanta, United States

    2 h-index

    5 publications

    104 citations

  2. Bristol-Myers Squibb (United States)

    New York, United States

    1 h-index

    14 publications

    266 citations

  3. Institute for Work and Health

    Lausanne, Switzerland

    1 h-index

    1 publications

    17 citations

  4. University of Basel

    Basel, Switzerland

    1 h-index

    3 publications

    51 citations

  5. Federal Department of Economic Affairs, Education and Research

    Bern, Switzerland

    1 h-index

    2 publications

    34 citations

  6. United States Food and Drug Administration

    Silver Spring, United States

    1 h-index

    3 publications

    105 citations

  7. Bioanalytica (Switzerland)

    Lucerne, Switzerland

    1 h-index

    14 publications

    266 citations

  8. Federal Office for Agriculture

    Liebefeld, Switzerland

    1 h-index

    1 publications

    17 citations

1–8 of 14

Venues

  1. Regulatory Toxicology and Pharmacology

    RTP · 5 publications · 118 citations

    5

    h-index

  2. 1

    h-index

1–2