Concepedia

Depot Effect

Depot Effect is a pharmacokinetic phenomenon in vaccine adjuvant design whereby an antigen reservoir is formed at the injection site, enabling prolonged antigen release and sustained immune stimulation.

172

Publications

8.1K

Citations

782

Authors

265

Institutions

Publications per year

2017–2026

13

Variants

Depot Effect Phenomenon

Parents

Publications

172

Omental and Subcutaneous Adipose Tissues of Obese Subjects Release Interleukin-6: Depot Difference and Regulation by Glucocorticoid

Susan K. Fried · The Journal of Clinical Endocrinology & Metabolism · 1998 · 1.1K citations

, , +15

Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation.

Matthew Adams, Carl Montague, Johannes B. Prins et al. · Journal of Clinical Investigation · 1997 · 520 citations · Full text

, , +17

Depot-specific differences in inflammatory mediators and a role for NK cells and IFN-γ in inflammation in human adipose tissue

Robert W. O’Rourke, Monja D. Metcalf, Ashley E. White et al. · International Journal of Obesity · 2009 · 198 citations

, , +17

Liposomes based on dimethyldioctadecylammonium promote a depot effect and enhance immunogenicity of soluble antigen

Malou Henriksen‐Lacey, Vincent W. Bramwell, Dennis Christensen et al. · Journal of Controlled Release · 2009 · 195 citations

, , +15

Targeted Codelivery of an Antigen and Dual Agonists by Hybrid Nanoparticles for Enhanced Cancer Immunotherapy

Linhua Zhang, Shengjie Wu, Yu Qin et al. · Nano Letters · 2019 · 188 citations

, , +17

1–5 of 172

Authors

782

  1. ML
    Maurice Landy

    National Cancer Institute, United States

    5 publications · 117 citations

    5

    h-index

  2. ME
    Marion E. Webster

    National Heart Lung and Blood Institute, United States

    4 publications · 74 citations

    4

    h-index

  3. HT
    Haruo Taniguchi

    Osaka International Cancer Institute, Japan

    4 publications · 91 citations

    4

    h-index

  4. MT
    Masaharu Tatsuta

    Osaka International Cancer Institute, Japan

    4 publications · 90 citations

    4

    h-index

  5. MB
    Miyako Baba

    Osaka International Cancer Institute, Japan

    3 publications · 76 citations

    3

    h-index

1–5 of 782

Institutions

265

  1. Osaka International Cancer Institute

    Osaka, Japan

    5 h-index

    9 publications

    176 citations

  2. University of Utah

    Salt Lake City, United States

    4 h-index

    7 publications

    301 citations

  3. University of Cambridge

    Cambridge, United Kingdom

    3 h-index

    17 publications

    4.6K citations

  4. Lundbeck (Denmark)

    Copenhagen, Denmark

    3 h-index

    8 publications

    207 citations

  5. United States Army

    Arlington, United States

    3 h-index

    11 publications

    218 citations

  6. Statens Serum Institut

    Copenhagen, Denmark

    3 h-index

    14 publications

    1.6K citations

  7. Copenhagen University Hospital

    Copenhagen, Denmark

    2 h-index

    10 publications

    180 citations

  8. Bicêtre Hospital

    Le Kremlin-Bicêtre, France

    2 h-index

    3 publications

    69 citations

1–8 of 265

Venues

  1. PubMed

    Repository · 18 publications · 391 citations

    14

    h-index

  2. European Journal of Endocrinology

    EJE · 4 publications · 117 citations

    4

    h-index

  3. Journal of Controlled Release

    4 publications · 302 citations

    4

    h-index

  4. Allergy

    4 publications · 80 citations

    4

    h-index

  5. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 4 publications · 1.3K citations

    4

    h-index

1–5