Concepedia

Deletional Tolerance

Deletional Tolerance is a mechanistic immunological process, within the broader category of transplant tolerance, characterized by the permanent elimination of alloreactive T cells through apoptosis or clonal deletion, thereby preventing adaptive immune responses against transplanted antigens.

27

Publications

1.9K

Citations

177

Authors

55

Institutions

Publications per year

2017–2026

3

Parents

Publications

27

Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells

James M. Gardner, Jason DeVoss, Rachel S. Friedman et al. · Science · 2008 · 483 citations · Full text

, , +17

CD8 T cell ignorance or tolerance to islet antigens depends on antigen dose

Christian Kurts, Robyn M. Sutherland, Gayle M. Davey et al. · Proceedings of the National Academy of Sciences · 1999 · 242 citations

, , +17

Skin-Derived Dendritic Cells Can Mediate Deletional Tolerance of Class I-Restricted Self-Reactive T Cells

Jason Waithman, Rhys S. Allan, Hiroshi Kosaka et al. · The Journal of Immunology · 2007 · 122 citations

, , +17

Donor-specific transplantation tolerance: The paradoxical behavior of CD4 <sup>+</sup> CD25 <sup>+</sup> T cells

Luís Graça, Alaín Le Moine, Chun‐Yen Lin et al. · Proceedings of the National Academy of Sciences · 2004 · 106 citations · Full text

, , +17

Soluble Antigen and CD40 Triggering Are Sufficient to Induce Primary and Memory Cytotoxic T Cells

Leo Lefrançois, John D. Altman, Kristina Williams et al. · The Journal of Immunology · 2000 · 104 citations · Full text

, , +17

1–5 of 27

Authors

177

  1. MS
    Megan Sykes

    Massachusetts General Hospital, United States

    3 publications · 166 citations

    3

    h-index

  2. WR
    William R. Heath

    Walter and Eliza Hall Institute of Medical Research, Australia

    3 publications · 387 citations

    3

    h-index

  3. JC
    Joren C. Madsen

    Massachusetts General Hospital, United States

    2 publications · 32 citations

    2

    h-index

  4. CK
    Christian Kurts

    University of Bonn, Germany

    2 publications · 265 citations

    2

    h-index

  5. TH
    Timothy Hogan

    Harvard University, United States

    2 publications · 93 citations

    2

    h-index

1–5 of 177

Institutions

55

  1. Massachusetts General Hospital

    Boston, United States

    8 h-index

    38 publications

    1.5K citations

  2. Harvard University

    Cambridge, United States

    7 h-index

    32 publications

    1.5K citations

  3. University of California, San Francisco

    San Francisco, United States

    4 h-index

    23 publications

    5.6K citations

  4. Walter and Eliza Hall Institute of Medical Research

    Melbourne, Australia

    4 h-index

    23 publications

    2.9K citations

  5. The University of Melbourne

    Melbourne, Australia

    3 h-index

    12 publications

    744 citations

  6. Stanford University

    Stanford, United States

    2 h-index

    13 publications

    5.4K citations

  7. Center for Systems Biology

    Boston, United States

    1 h-index

    1 publications

    73 citations

  8. UConn Health

    Farmington, United States

    1 h-index

    3 publications

    312 citations

1–8 of 55

Venues

  1. The Journal of Immunology

    JI · 9 publications · 474 citations

    9

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 598 citations

    7

    h-index

  3. Cell Transplantation

    1 publications · 17 citations

    1

    h-index

  4. Blood

    1 publications · 64 citations

    1

    h-index

  5. PubMed

    Repository · 1 publications · 12 citations

    1

    h-index

1–5