Concepedia

Defense Islands

Defense Islands is a genomic construct denoting a clustered genomic region enriched with mobile genetic elements and associated defense-related genes that function collectively in prokaryotic innate immunity against foreign genetic invaders.

23

Publications

3.1K

Citations

101

Authors

55

Institutions

Publications per year

2017–2026

19

Parents

Publications

23

Systematic discovery of antiphage defense systems in the microbial pangenome

Shany Doron, Sarah Melamed, Gal Ofir et al. · Science · 2018 · 1.4K citations · Full text

, , +17

Defense Islands in Bacterial and Archaeal Genomes and Prediction of Novel Defense Systems

Kira S. Makarova, Yuri I. Wolf, Sagi Snir et al. · Journal of Bacteriology · 2011 · 524 citations · Full text

, , +15

A functional selection reveals previously undetected anti-phage defence systems in the E. coli pangenome

Christopher N. Vassallo, Christopher R. Doering, Megan L. Littlehale et al. · Nature Microbiology · 2022 · 329 citations · Full text

, , +16

Temporal shifts in antibiotic resistance elements govern phage-pathogen conflicts

Kristen N. LeGault, Stephanie G. Hays, Angus Angermeyer et al. · Science · 2021 · 170 citations

, , +17

The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses

David M. Picton, Yvette A. Luyten, Richard Morgan et al. · Nucleic Acids Research · 2021 · 110 citations · Full text

, , +17

1–5 of 23

Authors

101

  1. AB
    Aude Bernheim

    Institut Pasteur, France

    3 publications · 111 citations

    4

    h-index

  2. MT
    Michael T. Laub

    Massachusetts Institute of Technology, United States

    2 publications · 339 citations

    3

    h-index

  3. JB
    Joseph Bondy‐Denomy

    University of California, San Francisco, United States

    2 publications · 121 citations

    3

    h-index

  4. EH
    Erin Huiting

    National Institute of Allergy and Infectious Diseases, United States

    2 publications · 121 citations

    3

    h-index

  5. RS
    Rotem Sorek

    Weizmann Institute of Science, Israel

    3 publications · 1.5K citations

    3

    h-index

1–5 of 101

Institutions

55

  1. Université Paris Cité

    Paris, France

    5 h-index

    4 publications

    178 citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    10 publications

    596 citations

  3. Institut Pasteur

    Paris, France

    4 h-index

    9 publications

    395 citations

  4. Weizmann Institute of Science

    Rehovot, Israel

    3 h-index

    29 publications

    11.8K citations

  5. Quantitative BioSciences

    Solana Beach, United States

    3 h-index

    2 publications

    121 citations

  6. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    10 publications

    1.7K citations

  7. Inserm

    Paris, France

    3 h-index

    3 publications

    122 citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    2 publications

    339 citations

1–8 of 55

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 6 publications · 111 citations

    6

    h-index

  2. Nucleic Acids Research

    4 publications · 295 citations

    5

    h-index

  3. Science

    2 publications · 1.5K citations

    2

    h-index

  4. PLoS Genetics

    2 publications · 130 citations

    2

    h-index

  5. Korean Journal of Parasitology

    1 publications · 13 citations

    1

    h-index

1–5