Concepedia

Default Neural Fate Model

The Default Neural Fate Model is a theoretical framework in developmental neurobiology proposing that neural induction occurs passively as a default pathway in the absence of inhibitory signals, distinguishing it from inductive models requiring active signaling cues to specify neural cell fate.

11

Publications

930

Citations

57

Authors

19

Institutions

Publications per year

2017–2026

2

Variants

Default Model Of Neural InductionNeural Default Model

Parents

Publications

11

Embryonic stem cells assume a primitive neural stem cell fate in the absence of extrinsic influences

Simon R. Smukler, Susan Runciman, Shunbin Xu et al. · The Journal of Cell Biology · 2006 · 245 citations · Full text

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Neural induction requires BMP inhibition only as a late step, and involves signals other than FGF and Wnt antagonists

Claudia Linker, Claudio D. Stern · Development · 2004 · 202 citations

, , +17

BMP inhibition initiates neural induction via FGF signaling and Zic genes

Leslie Marchal, Guillaume Luxardi, Virginie Thomé et al. · Proceedings of the National Academy of Sciences · 2009 · 130 citations · Full text

, , +17

Cell fate determination in embryonic ectoderm.

Chenbei Chang, Ali Hemmati‐Brivanlou · PubMed · 1998 · 77 citations

, , +17

Cell fate determination in embryonic ectoderm

Chenbei Chang, Ali Hemmati‐Brivanlou · Journal of Neurobiology · 1998 · 72 citations

, , +17

1–5 of 11

Authors

57

  1. CC
    Chenbei Chang

    University of Alabama at Birmingham, United States

    2 publications · 149 citations

    2

    h-index

  2. AH
    Ali Hemmati‐Brivanlou

    Rockefeller University, United States

    2 publications · 149 citations

    2

    h-index

  3. CD
    Christiane Daguzan

    Centre de Biologie du Développement, France

    1 publications · 21 citations

    1

    h-index

  4. SG
    Sally G. Hoskins

    City College of New York, United States

    1 publications · 30 citations

    1

    h-index

  5. DV
    Derek van der Kooy

    University of Toronto, Canada

    1 publications · 245 citations

    1

    h-index

1–5 of 57

Institutions

19

  1. Rockefeller University

    New York, United States

    2 h-index

    3 publications

    221 citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    5 publications

    541 citations

  3. Institut de Biologie du Développement Marseille

    Marseille, France

    1 h-index

    4 publications

    520 citations

  4. Tokyo Institute of Technology

    Tokyo, Japan

    1 h-index

    12 publications

    504 citations

  5. Indiana University School of Medicine

    Indianapolis, United States

    1 h-index

    13 publications

    767 citations

  6. The Graduate Center, CUNY

    New York, United States

    1 h-index

    1 publications

    30 citations

  7. Monell Chemical Senses Center

    Philadelphia, United States

    1 h-index

    2 publications

    84 citations

  8. University College London

    London, United Kingdom

    1 h-index

    2 publications

    404 citations

1–8 of 19

Venues

  1. PubMed

    Repository · 3 publications · 128 citations

    3

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 189 citations

    2

    h-index

  3. Development

    1 publications · 202 citations

    1

    h-index

  4. Communications Biology

    1 publications · 42 citations

    1

    h-index

  5. Journal of Neurobiology

    1 publications · 72 citations

    1

    h-index

1–5