Concepedia

Cytoplasmic Gate Structure

Cytoplasmic Gate Structure is a structural framework in ion channel proteins that regulates ion flow by undergoing conformational changes at the intracellular entrance, distinguishing it from extracellular or pore-centric gating mechanisms through its specific localization and regulatory role in channel activation.

36

Publications

3.6K

Citations

186

Authors

88

Institutions

Publications per year

2017–2026

11

Parents

Publications

36

Acetylcholine Receptor Channel Structure Probed in Cysteine-Substitution Mutants

Myles H. Akabas, David A. Stauffer, Ming Xu et al. · Science · 1992 · 669 citations

, , +16

Putative receptor for the cytoplasmic inactivation gate in the Shaker K+ channel

Ehud Y. Isacoff, Yuh Nung Jan, Lily Yeh Jan · Nature · 1991 · 340 citations

, , +16

Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification

S.D. Pegan, Christine Arrabit, Wei Zhou et al. · Nature Neuroscience · 2005 · 288 citations

, , +8

Intracellular gate opening in Shaker K+ channels defined by high-affinity metal bridges

Sarah M. Webster, Donato del Camino, John P. Dekker et al. · Nature · 2004 · 206 citations

, , +15

Structure of the KcsA channel intracellular gate in the open state.

Yi‐Shiuan Liu, Pornthep Sompornpisut, Eduardo Perozo · Nature Structural Biology · 2001 · 194 citations

, , +7

1–5 of 36

Authors

186

  1. MH
    Myles H. Akabas

    Albert Einstein College of Medicine, United States

    3 publications · 872 citations

    3

    h-index

  2. MY
    Mariko Yokogawa

    The University of Tokyo, Japan

    2 publications · 59 citations

    2

    h-index

  3. MO
    Masanori Osawa

    The University of Tokyo, Japan

    2 publications · 59 citations

    2

    h-index

  4. LR
    Lucy R. Forrest

    National Institute of Neurological Disorders and Stroke, United States

    2 publications · 166 citations

    2

    h-index

  5. YM
    Yoko Mase

    The University of Tokyo, Japan

    2 publications · 59 citations

    2

    h-index

1–5 of 186

Institutions

88

  1. The University of Tokyo

    Tokyo, Japan

    2 h-index

    11 publications

    306 citations

  2. Japan Biological Informatics Consortium

    Tokyo, Japan

    2 h-index

    2 publications

    59 citations

  3. Salk Institute for Biological Studies

    La Jolla, United States

    2 h-index

    10 publications

    2K citations

  4. Columbia University

    New York, United States

    2 h-index

    7 publications

    3.1K citations

  5. Center for Life Sciences

    Beijing, China

    2 h-index

    5 publications

    503 citations

  6. University of South Australia

    Adelaide, Australia

    1 h-index

    2 publications

    62 citations

  7. Washington University in St. Louis

    St Louis, United States

    1 h-index

    7 publications

    910 citations

  8. Université de Bretagne Occidentale

    Brest, France

    1 h-index

    1 publications

    84 citations

1–8 of 88

Venues

  1. Nature Communications

    4 publications · 268 citations

    4

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 113 citations

    4

    h-index

  3. Journal of Biological Chemistry

    JBC · 3 publications · 105 citations

    3

    h-index

  4. The Journal of General Physiology

    JGP · 3 publications · 144 citations

    3

    h-index

  5. The EMBO Journal

    2 publications · 169 citations

    2

    h-index

1–5