Concepedia

Cytokine Neutralization

Cytokine Neutralization is a therapeutic intervention strategy that belongs to the class of immunomodulatory approaches, specifically characterized by the targeted inhibition of pro-inflammatory cytokines through monoclonal antibodies, soluble receptors, or antagonists to prevent their interaction with cellular receptors and thereby attenuate cytokine-mediated pathological inflammation.

135

Publications

8K

Citations

857

Authors

356

Institutions

Publications per year

2017–2026

42

Parents

Publications

135

Tralokinumab for moderate‐to‐severe atopic dermatitis: results from two 52‐week, randomized, double‐blind, multicentre, placebo‐controlled phase III trials (ECZTRA 1 and ECZTRA 2)*

Andreas Wollenberg, Andrew Blauvelt, Emma Guttman‐Yassky et al. · British Journal of Dermatology · 2020 · 595 citations · Full text

, , +16

Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes.

Fred D. Finkelman, Kathleen B. Madden, Suzanne C. Morris et al. · The Journal of Immunology · 1993 · 363 citations · Full text

, , +7

DAMP Signaling is a Key Pathway Inducing Immune Modulation after Brain Injury

Arthur Liesz, Alexander H. Dalpke, Éva Mracskó et al. · Journal of Neuroscience · 2015 · 332 citations · Full text

, , +17

Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines

Lang Rao, Shuai Xia, Wei Xu et al. · Proceedings of the National Academy of Sciences · 2020 · 258 citations · Full text

, , +17

Role for IL-10 in Suppression Mediated by Peptide-Induced Regulatory T Cells In Vivo

Anette Sundstedt, Emma J. O’Neill, Kirsty Nicolson et al. · The Journal of Immunology · 2003 · 248 citations

, , +17

1–5 of 135

Authors

857

  1. GV
    Grace V. Milton

    Mercer University, United States

    3 publications · 65 citations

    3

    h-index

  2. CW
    Carl W. Oettinger

    Mercer University Health Sciences Center, United States

    3 publications · 65 citations

    3

    h-index

  3. RT
    Robin Thorpe

    National Institute for Biological Standards and Control, United Kingdom

    3 publications · 95 citations

    3

    h-index

  4. GM
    Gerhard Müller‐Newen

    RWTH Aachen University, Germany

    2 publications · 33 citations

    2

    h-index

  5. LW
    Larry W. Moreland

    University of Alabama at Birmingham, United States

    2 publications · 26 citations

    2

    h-index

1–5 of 857

Institutions

356

  1. Inserm

    Paris, France

    5 h-index

    23 publications

    659 citations

  2. University of Copenhagen

    Copenhagen, Denmark

    4 h-index

    6 publications

    395 citations

  3. Novartis (Switzerland)

    Basel, Switzerland

    4 h-index

    13 publications

    424 citations

  4. Harvard University

    Cambridge, United States

    3 h-index

    5 publications

    497 citations

  5. University of Pittsburgh

    Pittsburgh, United States

    3 h-index

    14 publications

    374 citations

  6. McMaster University

    Hamilton, Canada

    3 h-index

    8 publications

    172 citations

  7. Institut de Biologie Moléculaire et Cellulaire

    Strasbourg, France

    2 h-index

    9 publications

    1.6K citations

  8. Stanford University

    Stanford, United States

    2 h-index

    5 publications

    848 citations

1–8 of 356

Venues

  1. The Journal of Immunology

    JI · 13 publications · 1.6K citations

    13

    h-index

  2. PubMed

    Repository · 7 publications · 240 citations

    7

    h-index

  3. mAbs

    3 publications · 191 citations

    3

    h-index

  4. Journal of Immunological Methods

    3 publications · 104 citations

    3

    h-index

  5. Frontiers in Immunology

    3 publications · 116 citations

    3

    h-index

1–5