Concepedia

Ctcf-mediated Looping

CTCF-Mediated Looping is a molecular mechanism in chromatin architecture whereby the architectural protein CTCF facilitates the formation of stable DNA loops by binding to specific genomic sequences and recruiting cohesin to mediate long-range interactions that regulate gene expression and chromatin domain organization.

101

Publications

15.2K

Citations

688

Authors

299

Institutions

Publications per year

2017–2026

75

Parents

Publications

101

Cohesins Functionally Associate with CTCF on Mammalian Chromosome Arms

Vania Parelho, Suzana Hadjur, Mikhail Spivakov et al. · Cell · 2008 · 900 citations · Full text

, , +11

The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension

Judith H.I. Haarhuis, Robin H. van der Weide, Vincent A. Blomen et al. · Cell · 2017 · 861 citations · Full text

, , +17

Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells

Jessica Zuin, Jesse R. Dixon, Michael I. J. A. van der Reijden et al. · Proceedings of the National Academy of Sciences · 2013 · 820 citations

, , +17

CTCF Binding Polarity Determines Chromatin Looping

Elzo de Wit, Erica S.M. Vos, Sjoerd J.B. Holwerda et al. · Molecular Cell · 2015 · 702 citations · Full text

, , +12

CTCF mediates long-range chromatin looping and local histone modification in the β-globin locus

Erik Splinter, Helen Heath, Jurgen Kooren et al. · Genes & Development · 2006 · 701 citations · Full text

, , +17

1–5 of 101

Authors

688

  1. JP
    Jan‐Michael Peters

    Research Institute of Molecular Pathology, Austria

    7 publications · 973 citations

    7

    h-index

  2. IF
    Iain F. Davidson

    Research Institute of Molecular Pathology, Austria

    7 publications · 973 citations

    7

    h-index

  3. CC
    Claudia Cattoglio

    University of California, Berkeley, United States

    6 publications · 1.6K citations

    6

    h-index

  4. LA
    Leonid A. Mirny

    Massachusetts Institute of Technology, United States

    6 publications · 989 citations

    6

    h-index

  5. AS
    Anders S. Hansen

    Massachusetts Institute of Technology, United States

    6 publications · 1.6K citations

    6

    h-index

1–5 of 688

Institutions

299

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    11 h-index

    32 publications

    7.1K citations

  2. Massachusetts Institute of Technology

    Cambridge, United States

    10 h-index

    22 publications

    4.4K citations

  3. University of California, Berkeley

    Berkeley, United States

    9 h-index

    33 publications

    8K citations

  4. Harvard University

    Cambridge, United States

    9 h-index

    13 publications

    816 citations

  5. Research Institute of Molecular Pathology

    Vienna, Austria

    7 h-index

    53 publications

    8.5K citations

  6. Broad Institute

    Cambridge, United States

    6 h-index

    13 publications

    2.4K citations

  7. Baylor College of Medicine

    Houston, United States

    6 h-index

    20 publications

    2.8K citations

  8. Rice University

    Houston, United States

    6 h-index

    10 publications

    1.2K citations

1–8 of 299

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 15 publications · 308 citations

    12

    h-index

  2. Nature Communications

    12 publications · 985 citations

    12

    h-index

  3. Molecular Cell

    7 publications · 1.9K citations

    7

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 2K citations

    6

    h-index

  5. Nature

    6 publications · 1.6K citations

    6

    h-index

1–5