Concepedia

Ctcf Boundary Elements

CTCF Boundary Elements is a genomic regulatory construct defined as a specific DNA sequence motif that serves as a binding site for the CTCF protein, functioning as a cis-acting barrier to loop extrusion by cohesin complexes and thereby delineating the boundaries of topologically associating domains in chromatin architecture.

30

Publications

2.4K

Citations

230

Authors

121

Institutions

Publications per year

2017–2026

17

Parents

Publications

30

Rapid movement and transcriptional re‐localization of human cohesin on DNA

Iain F. Davidson, Daniela Goetz, Maciej Zaczek et al. · The EMBO Journal · 2016 · 276 citations · Full text

, , +17

CTCF-mediated topological boundaries during development foster appropriate gene regulation

Varun Narendra, Milica Bulajić, Job Dekker et al. · Genes & Development · 2016 · 193 citations · Full text

, , +17

Conserved CTCF Insulator Elements Flank the Mouse and Human β-Globin Loci

Catherine M. Farrell, Adam G. West, Gary Felsenfeld · Molecular and Cellular Biology · 2002 · 184 citations · Full text

, , +16

The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries

Sarah Hsu, Thomas G. Gilgenast, Caroline Bartman et al. · Molecular Cell · 2017 · 159 citations · Full text

, , +11

A Complex Chromatin Landscape Revealed by Patterns of Nuclease Sensitivity and Histone Modification within the Mouse β-Globin Locus

Michael Bulger, Dirk Schübeler, M. A. Bender et al. · Molecular and Cellular Biology · 2003 · 157 citations · Full text

, , +16

1–5 of 30

Authors

230

  1. SH
    Suming Huang

    University of Florida, United States

    3 publications · 288 citations

    3

    h-index

  2. HL
    Huacheng Luo

    Pennsylvania State University, United States

    3 publications · 288 citations

    3

    h-index

  3. MX
    Mingjiang Xu

    Sylvester Comprehensive Cancer Center, United States

    2 publications · 244 citations

    2

    h-index

  4. PF
    Paul Flicek

    European Bioinformatics Institute, United Kingdom

    2 publications · 143 citations

    2

    h-index

  5. KS
    Klara Stefflova

    University of Pennsylvania, United States

    2 publications · 143 citations

    2

    h-index

1–5 of 230

Institutions

121

  1. Pennsylvania State University

    State College, United States

    4 h-index

    19 publications

    2.2K citations

  2. Broad Institute

    Cambridge, United States

    3 h-index

    10 publications

    436 citations

  3. Fred Hutch Cancer Center

    Seattle, United States

    3 h-index

    10 publications

    1K citations

  4. University of Florida

    Gainesville, United States

    3 h-index

    16 publications

    1.4K citations

  5. Florida College

    Temple Terrace, United States

    3 h-index

    14 publications

    1.2K citations

  6. Harvard University

    Cambridge, United States

    3 h-index

    11 publications

    446 citations

  7. Cincinnati Children's Hospital Medical Center

    Cincinnati, United States

    3 h-index

    3 publications

    145 citations

  8. Dana-Farber Cancer Institute

    Boston, United States

    2 h-index

    5 publications

    182 citations

1–8 of 121

Venues

  1. Molecular Cell

    4 publications · 419 citations

    4

    h-index

  2. Nucleic Acids Research

    3 publications · 141 citations

    3

    h-index

  3. Genome biology

    2 publications · 229 citations

    2

    h-index

  4. Molecular and Cellular Biology

    MCB · 2 publications · 341 citations

    2

    h-index

  5. Nature Communications

    2 publications · 146 citations

    2

    h-index

1–5