Concepedia

Crowding-induced Compaction

Crowding-Induced Compaction is a biophysical phenomenon in which the presence of high concentrations of macromolecular crowders in a solution reduces the available volume for a biomolecule, thereby promoting its compaction into a more condensed conformational state due to excluded volume effects.

60

Publications

3.9K

Citations

202

Authors

104

Institutions

Publications per year

2017–2026

26

Parents

Publications

60

Molecular crowding enhances native state stability and refolding rates of globular proteins

Margaret S. Cheung, Dmitri K. Klimov, D. Thirumalai · Proceedings of the National Academy of Sciences · 2005 · 574 citations · Full text

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Structure, function, and folding of phosphoglycerate kinase are strongly perturbed by macromolecular crowding

Apratim Dhar, Antonios Samiotakis, Simon Ebbinghaus et al. · Proceedings of the National Academy of Sciences · 2010 · 324 citations · Full text

, , +17

Effect of Dextran on Protein Stability and Conformation Attributed to Macromolecular Crowding

Kenji Sasahara, Peter McPhie, Allen P. Minton · Journal of Molecular Biology · 2003 · 319 citations

, , +16

A role for macromolecular crowding effects in the assembly and function of compartments in the nucleus

Ronald Hancock · Journal of Structural Biology · 2004 · 166 citations

, , +12

Molecular Crowding Tunes Material States of Ribonucleoprotein Condensates

Taranpreet Kaur, Ibraheem Alshareedah, Wei Wang et al. · Biomolecules · 2019 · 155 citations · Full text

, , +17

1–5 of 60

Authors

202

  1. MS
    Margaret S. Cheung

    University of Houston, United States

    5 publications · 971 citations

    5

    h-index

  2. DT
    D. Thirumalai

    University of Maryland, College Park, United States

    4 publications · 679 citations

    4

    h-index

  3. BH
    Bae‐Yeun Ha

    University of Waterloo, Canada

    3 publications · 152 citations

    3

    h-index

  4. SV
    Sergey V. Dmitriev

    Institute of Metal Superplasticity Problems, Russia

    3 publications · 84 citations

    3

    h-index

  5. AS
    Andrea Soranno

    Washington University in St. Louis, United States

    3 publications · 113 citations

    3

    h-index

1–5 of 202

Institutions

104

  1. University of Maryland, College Park

    College Park, United States

    4 h-index

    9 publications

    1.9K citations

  2. National University of Singapore

    Singapore, Singapore

    4 h-index

    10 publications

    437 citations

  3. University of Waterloo

    Waterloo, Canada

    3 h-index

    7 publications

    379 citations

  4. Korea Institute for Advanced Study

    Seoul, South Korea

    3 h-index

    6 publications

    249 citations

  5. Institute of Metal Superplasticity Problems

    Ufa, Russia

    3 h-index

    6 publications

    168 citations

  6. National Institute of Diabetes and Digestive and Kidney Diseases

    Bethesda, United States

    3 h-index

    6 publications

    1.1K citations

  7. Nanyang Technological University

    Singapore, Singapore

    3 h-index

    6 publications

    161 citations

  8. Brandeis University

    Waltham, United States

    3 h-index

    6 publications

    204 citations

1–8 of 104

Venues

  1. Biophysical Journal

    8 publications · 516 citations

    8

    h-index

  2. Soft Matter

    4 publications · 173 citations

    4

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 1K citations

    3

    h-index

  4. Biochemical and Biophysical Research Communications

    BBRC · 3 publications · 50 citations

    3

    h-index

  5. The Journal of Physical Chemistry B

    3 publications · 88 citations

    3

    h-index

1–5