Crossover Hotspots is a genomic region characterized by a disproportionately high frequency of meiotic recombination events relative to the genomic average, thereby serving as a focal site for the exchange of genetic material between homologous chromosomes.
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Drive Against Hotspot Motifs in Primates Implicates the <i>PRDM9</i> Gene in Meiotic Recombination
Simon Myers, Rory Bowden, Afidalina Tumian et al. · Science · 2009 · 719 citations
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Jackson Laboratory
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