Concepedia

Crosslink Unhooking

Crosslink Unhooking is a DNA repair mechanism that cleaves one strand of a covalently linked interstrand crosslink adduct to permit replication or transcription machinery to bypass the lesion, thereby distinguishing it from complete crosslink excision or tolerance mechanisms.

9

Publications

778

Citations

40

Authors

23

Institutions

Publications per year

2017–2026

2

Parents

Publications

9

XPF-ERCC1 Acts in Unhooking DNA Interstrand Crosslinks in Cooperation with FANCD2 and FANCP/SLX4

Daisy Klein Douwel, Rick A.C.M. Boonen, David T. Long et al. · Molecular Cell · 2014 · 303 citations · Full text

, , +11

Replication-Dependent Unhooking of DNA Interstrand Cross-Links by the NEIL3 Glycosylase

Daniel R. Semlow, Jieqiong Zhang, Magda Budzowska et al. · Cell · 2016 · 207 citations

, , +14

Fanconi anaemia cells are not uniformly deficient in unhooking of DNA interstrand crosslinks, induced by mitomycin C or 8-methoxypsoralen plus UVA

E. H. A. Poll, F. Arwert, H. T. Kortbeek et al. · Human Genetics · 1984 · 61 citations

, , +14

Distortion-Dependent Unhooking of Interstrand Cross-Links in Mammalian Cell Extracts

Michael B. Smeaton, Erica M. Hlavin, Tracey McGregor Mason et al. · Biochemistry · 2008 · 52 citations · Full text

, , +15

FANCD2-associated Nuclease 1, but Not Exonuclease 1 or Flap Endonuclease 1, Is Able to Unhook DNA Interstrand Cross-links in Vitro

Julia Pizzolato, Shivam Mukherjee, Orlando D. Schärer et al. · Journal of Biological Chemistry · 2015 · 45 citations · Full text

, , +14

1–5 of 9

Authors

40

  1. JC
    Johannes C. Walter

    Harvard University, United States

    2 publications · 510 citations

    2

    h-index

  2. CJ
    Christopher J. Wilds

    Concordia University, Canada

    2 publications · 82 citations

    2

    h-index

  3. MB
    Michael B. Smeaton

    Johns Hopkins University, United States

    2 publications · 82 citations

    2

    h-index

  4. EM
    Erica M. Hlavin

    Concordia University, Canada

    2 publications · 82 citations

    2

    h-index

  5. AM
    Anne M. Noronha

    Concordia University, Canada

    2 publications · 82 citations

    2

    h-index

1–5 of 40

Institutions

23

  1. Concordia University

    Montreal, Canada

    2 h-index

    12 publications

    492 citations

  2. Harvard University

    Cambridge, United States

    2 h-index

    6 publications

    1.4K citations

  3. Johns Hopkins University

    Baltimore, United States

    2 h-index

    12 publications

    492 citations

  4. The Royal Free Hospital

    London, United Kingdom

    1 h-index

    2 publications

    62 citations

  5. Max Planck Institute of Biochemistry

    Martinsried, Germany

    1 h-index

    1 publications

    303 citations

  6. ETH Zurich

    Zurich, Switzerland

    1 h-index

    1 publications

    45 citations

  7. National Institutes of Health

    Bethesda, United States

    1 h-index

    2 publications

    46 citations

  8. National Institute of Environmental Health Sciences

    Durham, United States

    1 h-index

    2 publications

    46 citations

1–8 of 23

Venues

  1. Journal of Biological Chemistry

    JBC · 2 publications · 68 citations

    2

    h-index

  2. Chemical Research in Toxicology

    1 publications · 30 citations

    1

    h-index

  3. Cell

    1 publications · 207 citations

    1

    h-index

  4. Experimental Cell Research

    ECR · 1 publications · 31 citations

    1

    h-index

  5. Molecular Cell

    1 publications · 303 citations

    1

    h-index

1–5