Concepedia

Cross-substance Tolerance

Cross-Substance Tolerance is a pharmacological phenomenon in which tolerance developed to one substance results in a reduced response to another substance within the same class or with similar mechanisms of action, due to shared neurobiological pathways.

69

Publications

3.7K

Citations

184

Authors

64

Institutions

Publications per year

2017–2026

1

Variants

Cross-tolerance

Parents

Publications

69

Studies in the Primate on the Analgetic Effects Associated with Intrathecal Actions of Opiates,α-Adrenergic Agonists and Baclofen

Tony L. Yaksh, Sakamuri V. Reddy · Anesthesiology · 1981 · 528 citations

, , +15

Analgesic Effect of Morphine Glucuronides

Kyoichi Shimomura, Osamu Kamata, Showa Ueki et al. · The Tohoku Journal of Experimental Medicine · 1971 · 370 citations · Full text

, , +14

Paradoxical Effects after Microinjection of Morphine in the Periaqueductal Gray Matter in the Rat

Yasuko F. Jacquet, Ábel Lajtha · Science · 1974 · 269 citations

, , +17

Cross tolerance between morphine and methionine-enkephalin

Angela A. Waterfield, Joel W. Hughes, H. W. Kosterlitz · Nature · 1976 · 125 citations

, , +12

Cross tolerance between mescaline and LSD-25 with a comparison of the mescaline and LSD reactions

A. B. Wolbach, Harris Isbell, E. J. Miner · Psychopharmacology · 1962 · 104 citations

, , +6

1–5 of 69

Authors

184

  1. HI
    Harris Isbell

    United States Public Health Service, United States

    3 publications · 256 citations

    3

    h-index

  2. HK
    H. Kalant

    University of Toronto, Canada

    3 publications · 50 citations

    3

    h-index

  3. AB
    A. B. Wolbach

    National Institute of Mental Health, United States

    2 publications · 169 citations

    2

    h-index

  4. TL
    Tony L. Yaksh

    University of California San Diego, United States

    2 publications · 566 citations

    2

    h-index

  5. JK
    J.M. Khanna

    University of Toronto, Canada

    2 publications · 26 citations

    2

    h-index

1–5 of 184

Institutions

64

  1. National Institute of Mental Health

    Bethesda, United States

    3 h-index

    9 publications

    602 citations

  2. United States Department of Veterans Affairs

    Washington, United States

    3 h-index

    4 publications

    185 citations

  3. University of Colorado Boulder

    Boulder, United States

    2 h-index

    7 publications

    467 citations

  4. Texas College

    Tyler, United States

    2 h-index

    3 publications

    181 citations

  5. National Institute on Drug Abuse

    Bethesda, United States

    2 h-index

    6 publications

    214 citations

  6. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    5 publications

    143 citations

  7. Mario Negri Institute for Pharmacological Research

    Milan, Italy

    2 h-index

    10 publications

    365 citations

  8. New York University

    New York, United States

    2 h-index

    6 publications

    111 citations

1–8 of 64

Venues

  1. 12

    h-index

  2. Psychopharmacology

    12 publications · 715 citations

    12

    h-index

  3. PubMed

    Repository · 6 publications · 169 citations

    6

    h-index

  4. Pharmacology Biochemistry and Behavior

    6 publications · 220 citations

    6

    h-index

  5. Journal of Pharmacy and Pharmacology

    JPP · 4 publications · 122 citations

    4

    h-index

1–5