Concepedia

Coupled Folding

Coupled Folding is a molecular biophysical phenomenon in which the folding of an intrinsically disordered protein into a structured conformation is thermodynamically and kinetically linked to its binding interaction with a biological partner.

83

Publications

6.4K

Citations

292

Authors

132

Institutions

Publications per year

2017–2026

21

Variants

Coupled Folding And Binding

Parents

Publications

83

Mechanism of coupled folding and binding of an intrinsically disordered protein

Kenji Sugase, H. Jane Dyson, Peter E. Wright · Nature · 2007 · 1K citations

, , +12

Prediction of Protein Binding Regions in Disordered Proteins

Bálint Mészáros, István Simon, Zsuzsanna Dosztányi · PLoS Computational Biology · 2009 · 644 citations · Full text

, , +17

Kinetic Advantage of Intrinsically Disordered Proteins in Coupled Folding–Binding Process: A Critical Assessment of the “Fly-Casting” Mechanism

Yongqi Huang, Zhirong Liu · Journal of Molecular Biology · 2009 · 269 citations

, , +17

Quantifying why urea is a protein denaturant, whereas glycine betaine is a protein stabilizer

Emily J. Guinn, Laurel M. Pegram, Michelle N. Pollock et al. · Proceedings of the National Academy of Sciences · 2011 · 232 citations · Full text

, , +17

Binding-Induced Folding of a Natively Unstructured Transcription Factor

Adrián G. Turjanski, J. Silvio Gutkind, Robert B. Best et al. · PLoS Computational Biology · 2008 · 203 citations · Full text

, , +17

1–5 of 83

Authors

292

  1. JC
    Jane Clarke

    University of Cambridge, United Kingdom

    7 publications · 430 citations

    7

    h-index

  2. SL
    Sarah L. Shammas

    University of Cambridge, United Kingdom

    5 publications · 223 citations

    5

    h-index

  3. JW
    Jin Wang

    Stony Brook University, United States

    4 publications · 188 citations

    4

    h-index

  4. SA
    Scott A. Showalter

    Pennsylvania State University, United States

    3 publications · 95 citations

    3

    h-index

  5. PJ
    Per Jemth

    Uppsala University, Sweden

    3 publications · 228 citations

    3

    h-index

1–5 of 292

Institutions

132

  1. University of Cambridge

    Cambridge, United Kingdom

    10 h-index

    24 publications

    1.5K citations

  2. State University of New York

    Albany, United States

    4 h-index

    5 publications

    211 citations

  3. Uppsala University

    Uppsala, Sweden

    4 h-index

    10 publications

    600 citations

  4. Peking University

    Beijing, China

    4 h-index

    10 publications

    726 citations

  5. Chinese Academy of Sciences

    Beijing, China

    4 h-index

    7 publications

    450 citations

  6. Changchun Institute of Applied Chemistry

    Changchun, China

    4 h-index

    7 publications

    450 citations

  7. Stony Brook University

    Stony Brook, United States

    4 h-index

    5 publications

    211 citations

  8. University of Zurich

    Zurich, Switzerland

    4 h-index

    15 publications

    1.2K citations

1–8 of 132

Venues

  1. Journal of the American Chemical Society

    JACS · 10 publications · 783 citations

    10

    h-index

  2. Biochemistry

    9 publications · 356 citations

    9

    h-index

  3. Journal of Molecular Biology

    JMB · 7 publications · 601 citations

    7

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 617 citations

    6

    h-index

  5. Journal of Biological Chemistry

    JBC · 4 publications · 214 citations

    4

    h-index

1–5