Concepedia

Countercurrent Multiplication

Countercurrent Multiplication is a physiological mechanism in the renal medulla that establishes and maintains a hypertonic interstitial gradient through the active transport of sodium ions in the thick ascending limb of the loop of Henle, coupled with the countercurrent arrangement of tubular flow, thereby enabling the kidney to concentrates urine.

44

Publications

3.1K

Citations

136

Authors

57

Institutions

Publications per year

2017–2026

2

Parents

Publications

44

Micropuncture study of the mammalian urinary concentrating mechanism: evidence for the countercurrent hypothesis

Carl W. Gottschalk, Margaret Mylle · American Journal of Physiology-Legacy Content · 1959 · 589 citations

, , +16

Countercurrent multiplication system without active transport in inner medulla

Juha P. Kokko, Floyd C. Rector · Kidney International · 1972 · 505 citations · Full text

, , +9

Structure and concentrating mechanism in the mammalian kidney

Bodil Schmidt‐Nielsen, Roberta O'Dell · American Journal of Physiology-Legacy Content · 1961 · 277 citations

, , +17

Present knowledge of the counter-current system in the mammalian kidney

K. J. Ullrich, K. Krämer, John W. Boylan · Progress in Cardiovascular Diseases · 1961 · 180 citations

, , +13

Countercurrent multiplication by the thin loops of Henle

R. R. Jamison, C L Bennett, Berliner Rw · American Journal of Physiology-Legacy Content · 1967 · 126 citations

, , +2

1–5 of 44

Authors

136

  1. MJ
    Mats Jodal

    University of Gothenburg, Sweden

    6 publications · 206 citations

    6

    h-index

  2. HE
    Harold E. Layton

    Duke University, United States

    4 publications · 217 citations

    4

    h-index

  3. OL
    Ove Lundgren

    University of Gothenburg, Sweden

    3 publications · 141 citations

    3

    h-index

  4. MA
    Mark A. Knepper

    National Heart Lung and Blood Institute, United States

    3 publications · 185 citations

    3

    h-index

  5. DH
    Dan‐Axel Hallbäck

    University of Gothenburg, Sweden

    3 publications · 129 citations

    3

    h-index

1–5 of 136

Institutions

57

  1. University of Gothenburg

    Gothenburg, Sweden

    5 h-index

    14 publications

    604 citations

  2. University of Arizona

    Tucson, United States

    5 h-index

    11 publications

    513 citations

  3. Duke University

    Durham, United States

    5 h-index

    11 publications

    1K citations

  4. National Heart Lung and Blood Institute

    Bethesda, United States

    4 h-index

    9 publications

    377 citations

  5. The University of Texas Southwestern Medical Center

    Dallas, United States

    2 h-index

    3 publications

    1K citations

  6. National Institutes of Health

    Bethesda, United States

    2 h-index

    4 publications

    140 citations

  7. Cornell University

    Ithaca, United States

    2 h-index

    4 publications

    148 citations

  8. University of Michigan

    Ann Arbor, United States

    2 h-index

    4 publications

    70 citations

1–8 of 57

Venues

  1. 7

    h-index

  2. Acta Physiologica Scandinavica

    APS · 5 publications · 196 citations

    5

    h-index

  3. PubMed

    Repository · 5 publications · 215 citations

    5

    h-index

  4. American Journal of Physiology-Legacy Content

    4 publications · 1K citations

    4

    h-index

  5. Journal of the American Society of Nephrology

    3 publications · 213 citations

    3

    h-index

1–5