Concepedia

Cotranslational Targeting

Cotranslational Targeting is a protein targeting mechanism in which the translocation of a nascent polypeptide chain into the endoplasmic reticulum occurs simultaneously with its synthesis by the ribosome, thereby distinguishing it from post-translational targeting processes that follow complete protein synthesis.

81

Publications

5.4K

Citations

311

Authors

103

Institutions

Publications per year

2017–2026

13

Parents

Publications

81

Heterodimeric GTPase Core of the SRP Targeting Complex

Pamela J. Focia, Irina V. Shepotinovskaya, James A. Seidler et al. · Science · 2004 · 255 citations

, , +15

Defining the physiological role of SRP in protein-targeting efficiency and specificity

Elizabeth A. Costa, Kelly Subramanian, Jodi Nunnari et al. · Science · 2018 · 232 citations · Full text

, , +17

Signal sequences directing cotranslational translocation expand the range of proteins amenable to phage display

Daniel Steiner, Patrik Forrer, Michael T. Stumpp et al. · Nature Biotechnology · 2006 · 211 citations

, , +9

A novel signal recognition particle targets light-harvesting proteins to the thylakoid membranes

Danja Schuenemann, Shalini Gupta, Fabienne Cartieaux et al. · Proceedings of the National Academy of Sciences · 1998 · 203 citations · Full text

, , +17

Reciprocal stimulation of GTP hydrolysis by two directly interacting GTPases

Ted Powers, Peter Walter · Science · 1995 · 202 citations

, , +14

1–5 of 81

Authors

311

  1. SS
    Shu‐ou Shan

    California Institute of Technology, United States

    16 publications · 727 citations

    14

    h-index

  2. PW
    Peter Walter

    University of California, San Francisco, United States

    11 publications · 872 citations

    11

    h-index

  3. KS
    Katharina Strub

    University of Geneva, Switzerland

    4 publications · 219 citations

    4

    h-index

  4. SC
    Sowmya Chandrasekar

    California Institute of Technology, United States

    4 publications · 163 citations

    4

    h-index

  5. DF
    Douglas Freymann

    Northwestern University, United States

    4 publications · 446 citations

    4

    h-index

1–5 of 311

Institutions

103

  1. California Institute of Technology

    Pasadena, United States

    13 h-index

    48 publications

    2K citations

  2. University of California, San Francisco

    San Francisco, United States

    10 h-index

    35 publications

    2.5K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    16 publications

    920 citations

  4. University of Freiburg

    Freiburg im Breisgau, Germany

    4 h-index

    16 publications

    824 citations

  5. Northwestern University

    Evanston, United States

    3 h-index

    9 publications

    1.2K citations

  6. University of California San Francisco Medical Center

    San Francisco, United States

    3 h-index

    9 publications

    1K citations

  7. Heidelberg University

    Heidelberg, Germany

    3 h-index

    11 publications

    916 citations

  8. National Institutes of Health

    Bethesda, United States

    3 h-index

    6 publications

    388 citations

1–8 of 103

Venues

  1. The Journal of Cell Biology

    JCB · 12 publications · 893 citations

    12

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 655 citations

    8

    h-index

  3. Molecular Biology of the Cell

    MBC · 8 publications · 350 citations

    8

    h-index

  4. Journal of Biological Chemistry

    JBC · 6 publications · 306 citations

    6

    h-index

  5. RNA

    6 publications · 251 citations

    6

    h-index

1–5