Concepedia

Copper Neurotoxicity

Copper Neurotoxicity is a form of metal-induced neurotoxicity characterized by neuronal damage and dysfunction resulting specifically from the accumulation of copper ions in the central nervous system, disrupting cellular homeostasis through oxidative stress, mitochondrial impairment, and protein misfolding.

1.4K

Publications

85.3K

Citations

5.8K

Authors

1.5K

Institutions

Publications per year

2017–2026

354

Parents

Publications

1.4K

Copper, iron and zinc in Alzheimer's disease senile plaques

Mark A. Lovell, J. David Robertson, W.J. Teesdale et al. · Journal of the Neurological Sciences · 1998 · 2.1K citations

, , +12

Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

Robert A. Cherny, Craig Atwood, Michel Xilinas et al. · Neuron · 2001 · 1.5K citations · Full text

, , +13

Metal-triggered Structural Transformations, Aggregation, and Fibrillation of Human α-Synuclein

Vladimir N. Uversky, Jie Li, Anthony L. Fink · Journal of Biological Chemistry · 2001 · 1.1K citations · Full text

, , +16

Dramatic Aggregation of Alzheimer Aβ by Cu(II) Is Induced by Conditions Representing Physiological Acidosis

Craig Atwood, Robert D. Moir, Xudong Huang et al. · Journal of Biological Chemistry · 1998 · 1K citations · Full text

, , +17

Metal-Protein Attenuation With Iodochlorhydroxyquin (Clioquinol) Targeting Aβ Amyloid Deposition and Toxicity in Alzheimer Disease

Craig Ritchie, Ashley I. Bush, Andrew Mackinnon et al. · Archives of Neurology · 2003 · 982 citations

, , +17

1–5 of 1.4K

Authors

5.8K

  1. AI
    Ashley I. Bush

    The University of Melbourne, Australia

    34 publications · 8.4K citations

    29

    h-index

  2. CL
    Colin L. Masters

    The University of Melbourne, Australia

    29 publications · 7.6K citations

    27

    h-index

  3. RC
    Roberto Cappai

    The University of Melbourne, Australia

    24 publications · 3.1K citations

    20

    h-index

  4. AR
    Anthony R. White

    The University of Melbourne, Australia

    19 publications · 2.4K citations

    18

    h-index

  5. GM
    Gerd Multhaup

    Heidelberg University, Germany

    17 publications · 3.2K citations

    17

    h-index

1–5 of 5.8K

Institutions

1.5K

  1. The University of Melbourne

    Melbourne, Australia

    43 h-index

    301 publications

    56.6K citations

  2. Mental Health Research Institute

    Melbourne, Australia

    36 h-index

    162 publications

    37.8K citations

  3. Heidelberg University

    Heidelberg, Germany

    22 h-index

    42 publications

    11.9K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    20 h-index

    77 publications

    4.2K citations

  5. Chinese Academy of Sciences

    Beijing, China

    19 h-index

    75 publications

    15.1K citations

  6. Laboratoire de Chimie de Coordination

    Toulouse, France

    19 h-index

    57 publications

    3.4K citations

  7. Florey Institute of Neuroscience and Mental Health

    Melbourne, Australia

    17 h-index

    47 publications

    3.6K citations

  8. University of Chile

    Santiago, Chile

    16 h-index

    64 publications

    5.7K citations

1–8 of 1.5K

Venues

  1. Aquatic Toxicology

    46 publications · 3.4K citations

    35

    h-index

  2. Journal of Biological Chemistry

    JBC · 25 publications · 6.6K citations

    25

    h-index

  3. Ecotoxicology and Environmental Safety

    EES · 37 publications · 1.9K citations

    24

    h-index

  4. Journal of Neurochemistry

    JNC · 26 publications · 2.1K citations

    22

    h-index

  5. Biological Trace Element Research

    38 publications · 1.5K citations

    22

    h-index

1–5