Concepedia

Cooperativity Modeling

Cooperativity Modeling is a computational or mathematical framework that describes the phenomenon in which the binding of a ligand to one subunit of a multimeric protein influences the binding affinity of neighboring subunits, thereby capturing the allosteric interactions that underlie cooperative behavior in biological systems.

93

Publications

4.4K

Citations

308

Authors

152

Institutions

Publications per year

2017–2026

22

Parents

Publications

93

The mobile receptor hypothesis and “cooperativity” of hormone binding. Application to insulin

Steven Jacobs, Pedro Cuatrecasas · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1976 · 256 citations

, , +15

Transients and Cooperativity

Garrett R. Ainslie, Jonathan P. Shill, Kenneth Neet · Journal of Biological Chemistry · 1972 · 241 citations · Full text

, , +17

Photon storage in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>Λ</mml:mi></mml:math>-type optically dense atomic media. I. Cavity model

Alexey V. Gorshkov, A. André, Mikhail D. Lukin et al. · Physical Review A · 2007 · 231 citations · Full text

, , +10

Ca2+ binding and conformational change in two series of point mutations to the individual Ca(2+)-binding sites of calmodulin.

John F. Maune, Claude B. Klee, Kathleen Beckingham · Journal of Biological Chemistry · 1992 · 214 citations · Full text

, , +16

Insulin binding to the human lymphocyte receptor. Evaluation of the negative cooperativity model.

R J Pollet, Mary L. Standaert, B.A. Haase · Journal of Biological Chemistry · 1977 · 205 citations · Full text

, , +14

1–5 of 93

Authors

308

  1. SR
    Shridhar R. Gadre

    Savitribai Phule Pune University, India

    3 publications · 122 citations

    4

    h-index

  2. MM
    Milind M. Deshmukh

    Dr. Hari Singh Gour University, India

    3 publications · 122 citations

    4

    h-index

  3. MB
    Mini Bharati Ahirwar

    Dr. Hari Singh Gour University, India

    3 publications · 122 citations

    4

    h-index

  4. WS
    Wen-jing Shi

    Shanxi Medical University, China

    3 publications · 34 citations

    3

    h-index

  5. PJ
    Pim J. de Vink

    Eindhoven University of Technology, Netherlands

    2 publications · 69 citations

    2

    h-index

1–5 of 308

Institutions

152

  1. Dr. Hari Singh Gour University

    Saugor, India

    4 h-index

    7 publications

    279 citations

  2. Savitribai Phule Pune University

    Pune, India

    4 h-index

    4 publications

    150 citations

  3. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    6 publications

    214 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    5 publications

    299 citations

  5. Shanxi Medical University

    Taiyuan, China

    3 h-index

    6 publications

    64 citations

  6. University of Geneva

    Geneva, Switzerland

    2 h-index

    8 publications

    203 citations

  7. Taiyuan University of Technology

    Taiyuan, China

    2 h-index

    8 publications

    96 citations

  8. Rice University

    Houston, United States

    2 h-index

    5 publications

    664 citations

1–8 of 152

Venues

  1. The Journal of Chemical Physics

    6 publications · 176 citations

    6

    h-index

  2. Journal of Biological Chemistry

    JBC · 4 publications · 683 citations

    4

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 211 citations

    4

    h-index

  4. The Journal of Physical Chemistry A

    4 publications · 159 citations

    4

    h-index

  5. Journal of Computational Chemistry

    2 publications · 101 citations

    3

    h-index

1–5