Concepedia

Cooperative Oxygen Binding

Cooperative Oxygen Binding is a physiological mechanism in hemoglobin wherein the binding of an oxygen molecule to one heme group increases the oxygen affinity of the remaining unoccupied heme groups within the same tetrameric complex, thereby facilitating efficient oxygen uptake and release in response to physiological gradients.

235

Publications

13K

Citations

603

Authors

207

Institutions

Publications per year

2017–2026

6

Parents

Publications

235

Stereochemistry of Cooperative Effects in Haemoglobin: Haem–Haem Interaction and the Problem of Allostery

M. F. Perutz · Nature · 1970 · 2.9K citations

, , +13

Stereochemistry of cooperative mechanisms in hemoglobin

M. F. Perutz, G. Fermi, Ben F. Luisi et al. · Accounts of Chemical Research · 1987 · 419 citations

, , +13

Coboglobins: Oxygen-Carrying Cobalt-Reconstituted Hemoglobin and Myoglobin

Brian M. Hoffman, David H. Petering · Proceedings of the National Academy of Sciences · 1970 · 255 citations · Full text

, , +16

Mechanism of tertiary structural change in hemoglobin.

Bruce R. Gelin, Martin Karplus · Proceedings of the National Academy of Sciences · 1977 · 215 citations · Full text

, , +15

A cooperative oxygen-binding hemoglobin from <i>Mycobacterium tuberculosis</i>

Manon Couture, Syun‐Ru Yeh, Beatrice A. Wittenberg et al. · Proceedings of the National Academy of Sciences · 1999 · 213 citations

, , +14

1–5 of 235

Authors

603

  1. KI
    Kiyohiro Imai

    The University of Osaka, Japan

    10 publications · 448 citations

    10

    h-index

  2. ML
    Michael L. Doyle

    New Frontier, United States

    8 publications · 190 citations

    8

    h-index

  3. HD
    Heinz Decker

    Johannes Gutenberg University Mainz, Germany

    8 publications · 455 citations

    8

    h-index

  4. GK
    Gary K. Ackers

    Washington University in St. Louis, United States

    8 publications · 192 citations

    8

    h-index

  5. WE
    William E. Royer

    University of Massachusetts Chan Medical School, United States

    7 publications · 258 citations

    7

    h-index

1–5 of 603

Institutions

207

  1. Sapienza University of Rome

    Rome, Italy

    12 h-index

    24 publications

    775 citations

  2. The University of Osaka

    Osaka, Japan

    10 h-index

    22 publications

    1.3K citations

  3. Johannes Gutenberg University Mainz

    Mainz, Germany

    9 h-index

    28 publications

    1.8K citations

  4. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    8 h-index

    16 publications

    4.2K citations

  5. University of Pennsylvania

    Philadelphia, United States

    7 h-index

    13 publications

    902 citations

  6. University of Toronto

    Toronto, Canada

    6 h-index

    15 publications

    438 citations

  7. University of Parma

    Parma, Italy

    6 h-index

    18 publications

    1.3K citations

  8. National Institutes of Health

    Bethesda, United States

    6 h-index

    13 publications

    937 citations

1–8 of 207

Venues

  1. Journal of Biological Chemistry

    JBC · 41 publications · 2.2K citations

    26

    h-index

  2. Biochemistry

    27 publications · 852 citations

    17

    h-index

  3. Journal of Molecular Biology

    JMB · 15 publications · 777 citations

    15

    h-index

  4. Journal of the American Chemical Society

    JACS · 11 publications · 461 citations

    11

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 11 publications · 1.3K citations

    10

    h-index

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