Concepedia

Consensus Mutagenesis

Consensus Mutagenesis is a protein engineering method that introduces mutations into a gene sequence based on the most frequent amino acid residues observed at each position in a multiple sequence alignment of homologous proteins, thereby leveraging evolutionary conservation to guide the design of functionally stable variants.

17

Publications

848

Citations

107

Authors

35

Institutions

Publications per year

2017–2026

7

Parents

Publications

17

Mutational Analysis of the Consensus Sequence of a Replication Origin from Yeast Chromosome III

J. Virginia van Houten, Carol S. Newlon · Molecular and Cellular Biology · 1990 · 170 citations

, , +15

Construction of stabilized proteins by combinatorial consensus mutagenesis

N Amin, A D Liu, S Ramer et al. · Protein Engineering Design and Selection · 2004 · 136 citations · Full text

, , +17

Mutational analysis of the consensus sequence of a replication origin from yeast chromosome III.

Judith Van Houten, Carol S. Newlon · Molecular and Cellular Biology · 1990 · 89 citations

, , +14

A Consensus Motif in the RFX DNA Binding Domain and Binding Domain Mutants with Altered Specificity

P. Emery, Michel Strubin, Kay Hofmann et al. · Molecular and Cellular Biology · 1996 · 73 citations · Full text

, , +15

Enhancement of cellulosome-mediated deconstruction of cellulose by improving enzyme thermostability

Sarah Moraïs, Johanna Stern, Amaranta Kahn et al. · Biotechnology for Biofuels · 2016 · 68 citations · Full text

, , +15

1–5 of 17

Authors

107

  1. VS
    Volker Schellenberger

    Leipzig University, Germany

    3 publications · 190 citations

    3

    h-index

  2. LM
    Lehe Mei

    Zhejiang University, China

    2 publications · 48 citations

    2

    h-index

  3. PG
    Pete Gualfetti

    2 publications · 151 citations

    2

    h-index

  4. HW
    Hongpeng Wang

    Zhejiang University of Science and Technology, China

    2 publications · 48 citations

    2

    h-index

  5. LM
    Lilia M. Babé

    University of California, San Francisco, United States

    2 publications · 54 citations

    2

    h-index

1–5 of 107

Institutions

35

  1. Chinese Academy of Sciences

    Beijing, China

    2 h-index

    5 publications

    81 citations

  2. Zhejiang University of Science and Technology

    Hangzhou, China

    2 h-index

    11 publications

    265 citations

  3. Ningbo University

    Ningbo, China

    2 h-index

    2 publications

    48 citations

  4. Ningbo University of Technology

    Ningbo, China

    2 h-index

    6 publications

    144 citations

  5. Rutgers, The State University of New Jersey

    New Brunswick, United States

    2 h-index

    4 publications

    518 citations

  6. Weizmann Institute of Science

    Rehovot, Israel

    2 h-index

    13 publications

    730 citations

  7. Commonwealth Scientific and Industrial Research Organisation

    Canberra, Australia

    1 h-index

    3 publications

    51 citations

  8. Geneva College

    Beaver Falls, United States

    1 h-index

    4 publications

    292 citations

1–8 of 35

Venues

  1. Molecular and Cellular Biology

    MCB · 3 publications · 332 citations

    3

    h-index

  2. Protein Engineering Design and Selection

    PEDS · 3 publications · 180 citations

    3

    h-index

  3. Biochemistry

    2 publications · 63 citations

    2

    h-index

  4. Protein Science

    PS · 1 publications · 31 citations

    1

    h-index

  5. Biochimie

    1 publications · 16 citations

    1

    h-index

1–5