Concepedia

Conformational Mapping

Conformational Mapping is a computational method in pharmacophore modeling that identifies and characterizes the spatially distinct arrangements of a molecule's rotatable bonds to determine its bioactive conformation.

319

Publications

12.6K

Citations

1.4K

Authors

509

Institutions

Publications per year

2017–2026

39

Parents

Publications

319

Mapping the conformational wave of acetylcholine receptor channel gating

Claudio Grosman, Ming Zhou, Anthony Auerbach · Nature · 2000 · 334 citations

, , +14

GPCR activation mechanisms across classes and macro/microscales

Alexander S. Hauser, Albert J. Kooistra, Christian Munk et al. · Nature Structural & Molecular Biology · 2021 · 308 citations · Full text

, , +17

Multiple Peptide Synthesis Methods and Their Applications. New Synthetic Methods (87)

Günther Jung, Annette G. Beck‐Sickinger · Angewandte Chemie International Edition in English · 1992 · 291 citations

, , +7

Crystal Structure of Human RhoA in a Dominantly Active Form Complexed with a GTP Analogue

Kentaro Ihara, Sachiko Muraguchi, Masato Kato et al. · Journal of Biological Chemistry · 1998 · 216 citations · Full text

, , +17

Conformational analysis of flexible ligands in macromolecular receptor sites

Andrew R. Leach, Irwin D. Kuntz · Journal of Computational Chemistry · 1992 · 214 citations

, , +14

1–5 of 319

Authors

1.4K

  1. DF
    Dale F. Mierke

    Brown University, United States

    5 publications · 151 citations

    5

    h-index

  2. AJ
    Alan J. Waring

    University of California, Los Angeles, United States

    4 publications · 233 citations

    4

    h-index

  3. MG
    Murray Goodman

    University of California San Diego, United States

    4 publications · 124 citations

    4

    h-index

  4. LM
    Larry M. Gordon

    University of California, Los Angeles, United States

    4 publications · 233 citations

    4

    h-index

  5. MA
    Masayuki Amagai

    Keio University, Japan

    3 publications · 143 citations

    3

    h-index

1–5 of 1.4K

Institutions

509

  1. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    50 publications

    1.8K citations

  2. Technical University of Munich

    Munich, Germany

    7 h-index

    20 publications

    1K citations

  3. University of California San Diego

    San Diego, United States

    7 h-index

    22 publications

    715 citations

  4. Washington University in St. Louis

    St Louis, United States

    6 h-index

    17 publications

    520 citations

  5. University of Naples Federico II

    Naples, Italy

    6 h-index

    18 publications

    399 citations

  6. Keio University

    Tokyo, Japan

    5 h-index

    22 publications

    932 citations

  7. University of California, Los Angeles

    Los Angeles, United States

    5 h-index

    8 publications

    378 citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    4 h-index

    15 publications

    1K citations

1–8 of 509

Venues

  1. Journal of Medicinal Chemistry

    15 publications · 632 citations

    14

    h-index

  2. Journal of the American Chemical Society

    JACS · 12 publications · 634 citations

    12

    h-index

  3. Biopolymers

    12 publications · 376 citations

    12

    h-index

  4. Bioorganic & Medicinal Chemistry

    10 publications · 362 citations

    10

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 419 citations

    8

    h-index

1–5