Concepedia

Conditional Protein Design

Conditional Protein Design is a protein design methodology that specifies the generation of protein structures or sequences subject to user-defined constraints or environmental conditions, distinguishing it from unconditional design approaches by explicitly incorporating contextual or functional requirements into the design process.

7

Publications

494

Citations

33

Authors

16

Institutions

Publications per year

2017–2026

4

Parents

Publications

7

The switches.ELM Resource: A Compendium of Conditional Regulatory Interaction Interfaces

Kim Van Roey, Holger Dinkel, Robert J. Weatheritt et al. · Science Signaling · 2013 · 248 citations

, , +11

Recent advances in in vivo applications of intein-mediated protein splicing

Natalya I. Topilina, Kenneth V. Mills · Mobile DNA · 2014 · 98 citations · Full text

, , +13

Conditional language models enable the efficient design of proficient enzymes

Geraldene Munsamy, R. Illanes, Silvia Fruncillo et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2024 · 42 citations · Full text

, , +17

Conditional generative modeling for <i>de novo</i> protein design with hierarchical functions

Tim Kucera, Matteo Togninalli, Laetitia Meng-Papaxanthos · Bioinformatics · 2022 · 30 citations · Full text

, , +15

An intein-cassette integration approach used for the generation of a split TEVprotease activated by conditional protein splicing

Tim Sonntag, Henning D. Mootz · Molecular BioSystems · 2011 · 30 citations

, , +15

1–5 of 7

Authors

33

  1. LA
    Lukas A. Widmer

    ETH Zurich, Switzerland

    1 publications · 25 citations

    1

    h-index

  2. SP
    Sven Panke

    ETH Zurich, Switzerland

    1 publications · 25 citations

    1

    h-index

  3. LM
    Laetitia Meng-Papaxanthos

    Google (United States), United States

    1 publications · 30 citations

    1

    h-index

  4. RJ
    Robert J. Weatheritt

    University of Toronto, Canada

    1 publications · 248 citations

    1

    h-index

  5. KV
    Kenneth V. Mills

    College of the Holy Cross, United States

    1 publications · 98 citations

    1

    h-index

1–5 of 33

Institutions

16

  1. ETH Zurich

    Zurich, Switzerland

    2 h-index

    7 publications

    180 citations

  2. University at Albany, State University of New York

    Albany, United States

    1 h-index

    1 publications

    98 citations

  3. College of the Holy Cross

    Worcester, United States

    1 h-index

    1 publications

    98 citations

  4. European Molecular Biology Laboratory

    Hamburg, Germany

    1 h-index

    5 publications

    1.2K citations

  5. Columbia University

    New York, United States

    1 h-index

    1 publications

    25 citations

  6. Couleecap

    Westby, United States

    1 h-index

    3 publications

    126 citations

  7. Isomerase Therapeutics (United Kingdom)

    Cambridge, United Kingdom

    1 h-index

    3 publications

    126 citations

  8. Institut de Biologia Molecular de Barcelona

    Barcelona, Spain

    1 h-index

    3 publications

    126 citations

1–8 of 16

Venues

  1. ACS Central Science

    1 publications · 21 citations

    1

    h-index

  2. Bioinformatics

    1 publications · 30 citations

    1

    h-index

  3. Mobile DNA

    1 publications · 98 citations

    1

    h-index

  4. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 1 publications · 42 citations

    1

    h-index

  5. BMC Biology

    1 publications · 25 citations

    1

    h-index

1–5