Concepedia

Concentration-response Variability

Concentration-Response Variability is a pharmacodynamic construct that characterizes the interindividual differences in the magnitude of drug effect at a given plasma or tissue concentration, accounting for variability in the sensitivity or reactivity of biological systems to drug exposure.

63

Publications

3.3K

Citations

332

Authors

124

Institutions

Publications per year

2017–2026

13

Parents

Publications

63

Relative dominance of hydrologic versus biogeochemical factors on solute export across impact gradients

Sally Thompson, N. B. Basu, J. Lascurain et al. · Water Resources Research · 2011 · 333 citations · Full text

, , +17

A Comparison of Assay Performance Measures in Screening Assays: Signal Window, Z′ Factor, and Assay Variability Ratio

Philip W. Iversen, Brian J. Eastwood, G. Sitta Sittampalam et al. · SLAS DISCOVERY · 2006 · 244 citations

, , +13

Pharmacokinetics of hydroxychloroquine and chloroquine during treatment of rheumatic diseases

Daniel E. Furst · Lupus · 1996 · 238 citations

, , +13

Estimating Toxicity-Related Biological Pathway Altering Doses for High-Throughput Chemical Risk Assessment

Richard Judson, Robert J. Kavlock, R. Woodrow Setzer et al. · Chemical Research in Toxicology · 2011 · 203 citations

, , +17

Population-Based <i>in Vitro</i> Hazard and Concentration–Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study

Nour Abdo, Menghang Xia, Chad Brown et al. · Environmental Health Perspectives · 2015 · 134 citations · Full text

, , +16

1–5 of 63

Authors

332

  1. IR
    Ivan Rusyn

    University of North Carolina at Chapel Hill, United States

    2 publications · 188 citations

    2

    h-index

  2. NA
    Nour Abdo

    Jordan University of Science and Technology, Jordan

    2 publications · 188 citations

    2

    h-index

  3. OK
    Oksana Kosyk

    University of North Carolina at Chapel Hill, United States

    2 publications · 188 citations

    2

    h-index

  4. RR
    Raymond R. Tice

    National Institute of Environmental Health Sciences, United States

    2 publications · 188 citations

    2

    h-index

  5. MX
    Menghang Xia

    National Institutes of Health, United States

    2 publications · 188 citations

    2

    h-index

1–5 of 332

Institutions

124

  1. Environmental Protection Agency

    Washington, United States

    5 h-index

    32 publications

    2.7K citations

  2. National Institutes of Health

    Bethesda, United States

    3 h-index

    17 publications

    986 citations

  3. National Institute of Environmental Health Sciences

    Durham, United States

    3 h-index

    11 publications

    422 citations

  4. Research Triangle Park Foundation

    Durham, United States

    3 h-index

    19 publications

    2.3K citations

  5. University of Pennsylvania

    Philadelphia, United States

    3 h-index

    9 publications

    316 citations

  6. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    13 publications

    1K citations

  7. Hebrew University of Jerusalem

    Jerusalem, Israel

    2 h-index

    5 publications

    87 citations

  8. National Center for Environmental Assessment (EPA)

    Cincinnati, United States

    2 h-index

    2 publications

    164 citations

1–8 of 124

Venues

  1. Toxicological Sciences

    4 publications · 187 citations

    4

    h-index

  2. Archives of Toxicology

    2 publications · 59 citations

    2

    h-index

  3. Journal of Economic Entomology

    2 publications · 63 citations

    2

    h-index

  4. 2

    h-index

  5. Therapeutic Drug Monitoring

    2 publications · 89 citations

    2

    h-index

1–5