Concepedia

Computational Protein Engineering

Computational Protein Engineering is a computational methodology that systematically designs and optimizes protein structures and functions through algorithmic, statistical, or physical modeling approaches, distinguishing it from experimental or purely descriptive techniques in protein science.

68

Publications

3.8K

Citations

322

Authors

116

Institutions

Publications per year

2017–2026

25

Parents

Publications

68

Reverse engineering of the giant muscle protein titin

Hongbin Li, Wolfgang A. Linke, Andrés F. Oberhauser et al. · Nature · 2002 · 529 citations

, , +11

Navigating the protein fitness landscape with Gaussian processes

Philip A. Romero, Andreas Krause, Frances H. Arnold · Proceedings of the National Academy of Sciences · 2012 · 377 citations · Full text

, , +14

Protein Design is NP-hard

Niles A. Pierce, Erik Winfree · Protein Engineering Design and Selection · 2002 · 274 citations · Full text

, , +9

RosettaDesign server for protein design

Yi Liu, Brian Kuhlman · Nucleic Acids Research · 2006 · 228 citations · Full text

, , +15

On design principles for a molecular computer

Michael Conrad · Communications of the ACM · 1985 · 209 citations · Full text

, , +16

1–5 of 68

Authors

322

  1. DB
    David Baker

    University of Washington, United States

    4 publications · 150 citations

    4

    h-index

  2. BK
    Brian Kuhlman

    University of North Carolina at Chapel Hill, United States

    2 publications · 261 citations

    2

    h-index

  3. CO
    Carlos Outeiral

    University of Oxford, United Kingdom

    2 publications · 93 citations

    2

    h-index

  4. SB
    Sophie Barbe

    Centre National de la Recherche Scientifique, France

    2 publications · 82 citations

    2

    h-index

  5. DA
    David Allouche

    Centre National de la Recherche Scientifique, France

    2 publications · 82 citations

    2

    h-index

1–5 of 322

Institutions

116

  1. University of Washington

    Seattle, United States

    4 h-index

    16 publications

    529 citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    13 publications

    798 citations

  3. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    4 h-index

    8 publications

    579 citations

  4. École Polytechnique Fédérale de Lausanne

    Lausanne, Switzerland

    3 h-index

    7 publications

    536 citations

  5. Stanford University

    Stanford, United States

    3 h-index

    12 publications

    377 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    9 publications

    300 citations

  7. University of Manchester

    Manchester, United Kingdom

    3 h-index

    10 publications

    500 citations

  8. California Institute of Technology

    Pasadena, United States

    3 h-index

    6 publications

    1.3K citations

1–8 of 116

Venues

  1. Methods in molecular biology

    Book series · 4 publications · 78 citations

    4

    h-index

  2. Nature

    3 publications · 567 citations

    3

    h-index

  3. Protein Engineering Design and Selection

    PEDS · 3 publications · 332 citations

    3

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 481 citations

    3

    h-index

  5. Nucleic Acids Research

    2 publications · 264 citations

    2

    h-index

1–5