Concepedia

Complexity-generating Synthesis

Complexity-Generating Synthesis is a synthetic strategy within diversity-oriented synthesis that belongs to the class of molecular complexity enhancement methods, distinguished by its focus on rapidly increasing topological, stereochemical, and functional group complexity in small molecules through iterative, often cascade-based, chemical transformations.

53

Publications

4.1K

Citations

229

Authors

80

Institutions

Publications per year

2017–2026

15

Parents

Publications

53

Strategies for Innovation in Multicomponent Reaction Design

Bruce Ganem · Accounts of Chemical Research · 2009 · 1.2K citations · Full text

, , +14

Pairwise Use of Complexity-Generating Reactions in Diversity-Oriented Organic Synthesis

Dae-Sung Lee, Jason K. Sello, Stuart L. Schreiber · Organic Letters · 2000 · 240 citations

, , +14

Dendralenes Branch Out: Cross‐Conjugated Oligoenes Allow the Rapid Generation of Molecular Complexity

Henning Hopf, Michael S. Sherburn · Angewandte Chemie International Edition · 2012 · 171 citations

, , +12

Multicatalytic Asymmetric Synthesis of Complex Tetrahydrocarbazoles via a Diels–Alder/Benzoin Reaction Sequence

Yankai Liu, Manuel Nappi, Eduardo C. Escudero‐Adán et al. · Organic Letters · 2012 · 156 citations

, , +15

Combinatorial Discovery of Full-Color-Tunable Emissive Fluorescent Probes Using a Single Core Skeleton, 1,2-Dihydropyrrolo[3,4-β]indolizin-3-one

Eunha Kim, Minseob Koh, Jihoon Ryu et al. · Journal of the American Chemical Society · 2008 · 146 citations

, , +17

1–5 of 53

Authors

229

  1. JZ
    Jieping Zhu

    École Polytechnique Fédérale de Lausanne, Switzerland

    3 publications · 136 citations

    3

    h-index

  2. VS
    Vishwakarma Singh

    Indian Institute of Technology Bombay, India

    2 publications · 38 citations

    2

    h-index

  3. PS
    Pan‐Lin Shao

    Southern University of Science and Technology, China

    2 publications · 162 citations

    2

    h-index

  4. ER
    Eelco Ruijter

    Vrije Universiteit Amsterdam, Netherlands

    2 publications · 117 citations

    2

    h-index

  5. CD
    Christopher D. Vanderwal

    University of California, Irvine, United States

    2 publications · 166 citations

    2

    h-index

1–5 of 229

Institutions

80

  1. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    11 publications

    446 citations

  2. Institut de Chimie des Substances Naturelles

    Gif-sur-Yvette, France

    3 h-index

    8 publications

    319 citations

  3. Scripps Research Institute

    San Diego, United States

    3 h-index

    15 publications

    1.3K citations

  4. Institut Català d'Investigació Química

    Tarragona, Spain

    2 h-index

    6 publications

    734 citations

  5. Lanzhou University

    Lanzhou, China

    2 h-index

    8 publications

    355 citations

  6. Princeton University

    Princeton, United States

    2 h-index

    4 publications

    212 citations

  7. Université de Strasbourg

    Strasbourg, France

    2 h-index

    6 publications

    308 citations

  8. University of Warwick

    Coventry, United Kingdom

    2 h-index

    6 publications

    192 citations

1–8 of 80

Venues

  1. Journal of the American Chemical Society

    JACS · 6 publications · 334 citations

    6

    h-index

  2. Angewandte Chemie International Edition

    4 publications · 368 citations

    4

    h-index

  3. Organic Letters

    OL · 4 publications · 504 citations

    4

    h-index

  4. Organic & Biomolecular Chemistry

    4 publications · 97 citations

    4

    h-index

  5. European Journal of Organic Chemistry

    3 publications · 163 citations

    3

    h-index

1–5