Concepedia

Complex I Assembly

Complex I Assembly is a molecular biological process that constitutes the ordered incorporation and organization of nuclear- and mitochondrial-encoded subunits into the functional NADH:ubiquinone oxidoreductase complex (Complex I) of the mitochondrial electron transport chain, distinguishing it from the assembly of other respiratory chain complexes by its specific protein components, assembly factors, and stepwise intermediate formation.

218

Publications

18.5K

Citations

923

Authors

326

Institutions

Publications per year

2017–2026

45

Parents

Publications

218

Accessory subunits are integral for assembly and function of human mitochondrial complex I

David A. Stroud, Elliot Surgenor, Luke E. Formosa et al. · Nature · 2016 · 662 citations · Full text

, , +13

Atomic structure of the entire mammalian mitochondrial complex I

Karol Fiedorczuk, James A. Letts, Gianluca Degliesposti et al. · Nature · 2016 · 555 citations · Full text

, , +14

Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes

Irene López-Fabuel, Juliette Le Douce, Angela Logan et al. · Proceedings of the National Academy of Sciences · 2016 · 502 citations · Full text

, , +17

Respiratory Complex III Is Required to Maintain Complex I in Mammalian Mitochondria

Rebeca Acín‐Pérez, M. Pilar Bayona‐Bafaluy, Patricio Fernández‐Silva et al. · Molecular Cell · 2004 · 474 citations · Full text

, , +15

Bovine Complex I Is a Complex of 45 Different Subunits

Joe Carroll, Ian M. Fearnley, Mark Skehel et al. · Journal of Biological Chemistry · 2006 · 465 citations · Full text

, , +17

1–5 of 218

Authors

923

  1. UB
    Ulrich Brandt

    Goethe University Frankfurt, Germany

    15 publications · 1.9K citations

    15

    h-index

  2. TF
    Thorsten Friedrich

    University of Freiburg, Germany

    14 publications · 802 citations

    13

    h-index

  3. JH
    Judy Hirst

    Medical Research Council, United Kingdom

    12 publications · 1.8K citations

    12

    h-index

  4. AV
    Arnaldo Videira

    Universidade do Porto, Portugal

    14 publications · 429 citations

    12

    h-index

  5. VZ
    Volker Zickermann

    Goethe University Frankfurt, Germany

    11 publications · 767 citations

    11

    h-index

1–5 of 923

Institutions

326

  1. Medical Research Council

    London, United Kingdom

    19 h-index

    84 publications

    12.8K citations

  2. Radboud University Nijmegen

    Nijmegen, The Netherlands

    19 h-index

    94 publications

    10.2K citations

  3. Goethe University Frankfurt

    Frankfurt am Main, Germany

    18 h-index

    93 publications

    9.9K citations

  4. Radboud University Medical Center

    Nijmegen, The Netherlands

    16 h-index

    65 publications

    8.5K citations

  5. Heinrich Heine University Düsseldorf

    Düsseldorf, Germany

    16 h-index

    69 publications

    4.8K citations

  6. MRC Mitochondrial Biology Unit

    Cambridge, United Kingdom

    14 h-index

    52 publications

    5.5K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    40 publications

    3K citations

  8. Universidade do Porto

    Porto, Portugal

    12 h-index

    27 publications

    876 citations

1–8 of 326

Venues

  1. Journal of Biological Chemistry

    JBC · 19 publications · 2.2K citations

    19

    h-index

  2. 17

    h-index

  3. Journal of Molecular Biology

    JMB · 11 publications · 1.1K citations

    11

    h-index

  4. Human Molecular Genetics

    8 publications · 753 citations

    8

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 1.1K citations

    7

    h-index

1–5