Concepedia

Complement-mediated Rejection

Complement-Medshaled Rejection is a pathological immune response in kidney transplantation wherein donor-specific antibodies activate the complement cascade, leading to endothelial injury and acute graft dysfunction in the absence of adequate immunomodulation.

118

Publications

7.8K

Citations

744

Authors

212

Institutions

Publications per year

2017–2026

10

Parents

Publications

118

Capillary deposition of C4d complement fragment and early renal graft loss

Helmut E. Feucht, H. Schneeberger, Günther F. Hillebrand et al. · Kidney International · 1993 · 534 citations · Full text

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IMMUNOPATHOLOGY OF HYPERACUTE XENOGRAFT REJECTION IN A SWINE-TO-PRIMATE MODEL

Jeffrey L. Platt, Richard Fischel, Arthur J. Matas et al. · Transplantation · 1991 · 453 citations

, , +17

Expression of a functional human complement inhibitor in a transgenic pig as a model for the prevention of xenogeneic hyperacute organ rejection.

William L. Fodor, B. L. Williams, Louis A. Matis et al. · Proceedings of the National Academy of Sciences · 1994 · 348 citations

, , +17

TRANSGENIC PIGS EXPRESSING HUMAN CD59 AND DECAY-ACCELERATING FACTOR PRODUCE AN INTRINSIC BARRIER TO COMPLEMENT-MEDIATED DAMAGE1

Guerard W. Byrne, Kenneth R. McCurry, Michael J. Martin et al. · Transplantation · 1997 · 312 citations

, , +17

LIFE-SUPPORTING PIG-TO-PRIMATE RENAL XENOTRANSPLANTATION USING GENETICALLY MODIFIED DONORS

Afzal Zaidi, Michael Schmoeckel, Farah Bhatti et al. · Transplantation · 1998 · 268 citations

, , +17

1–5 of 118

Authors

744

  1. JL
    Jeffrey L. Platt

    Mayo Clinic, United States

    8 publications · 1.5K citations

    8

    h-index

  2. AP
    Agustin P. Dalmasso

    University of Minnesota, United States

    7 publications · 811 citations

    7

    h-index

  3. DJ
    David J. White

    University of Cambridge, United Kingdom

    6 publications · 430 citations

    6

    h-index

  4. FH
    Fritz H. Bach

    Harvard University, United States

    6 publications · 1.2K citations

    6

    h-index

  5. SA
    Scott A. Rollins

    Alexion Pharmaceuticals (United States), United States

    4 publications · 233 citations

    4

    h-index

1–5 of 744

Institutions

212

  1. University of Minnesota

    Minneapolis, United States

    7 h-index

    33 publications

    4.6K citations

  2. Harvard University

    Cambridge, United States

    6 h-index

    33 publications

    1.3K citations

  3. Massachusetts General Hospital

    Boston, United States

    6 h-index

    32 publications

    1.3K citations

  4. Alexion Pharmaceuticals (United States)

    Boston, United States

    5 h-index

    23 publications

    3.8K citations

  5. Papworth Hospital

    Cambridge, United Kingdom

    5 h-index

    17 publications

    2.1K citations

  6. St Vincent's Hospital Melbourne

    Melbourne, Australia

    4 h-index

    19 publications

    462 citations

  7. Heidelberg University

    Heidelberg, Germany

    4 h-index

    9 publications

    328 citations

  8. May Institute

    Randolph, United States

    4 h-index

    7 publications

    317 citations

1–8 of 212

Venues

  1. Transplantation

    42 publications · 3.3K citations

    29

    h-index

  2. PubMed

    Repository · 12 publications · 811 citations

    11

    h-index

  3. Xenotransplantation

    10 publications · 539 citations

    10

    h-index

  4. American Journal of Transplantation

    9 publications · 541 citations

    9

    h-index

  5. The Journal of Immunology

    JI · 4 publications · 156 citations

    4

    h-index

1–5