Concepedia

Complement System In Periodontitis

Complement System in Periodontitis is a pathophysiological mechanism within the host immune response that specifically mediates inflammation and tissue destruction in periodontal tissues through the dysregulated activation of complement cascades in the context of bacterial biofilm challenge.

56

Publications

3.2K

Citations

199

Authors

75

Institutions

Publications per year

2017–2026

7

Parents

Publications

56

Porphyromonas gingivalis Manipulates Complement and TLR Signaling to Uncouple Bacterial Clearance from Inflammation and Promote Dysbiosis

Tomoki Maekawa, Jennifer L. Krauss, Toshiharu Abe et al. · Cell Host & Microbe · 2014 · 420 citations · Full text

, , +17

Activation of complement components C3 and C5 by a cysteine proteinase (gingipain-1) from Porphyromonas (Bacteroides) gingivalis.

J.A. Wingrove, Richard G. DiScipio, Z Chen et al. · Journal of Biological Chemistry · 1992 · 252 citations · Full text

, , +17

Biphasic Effect of Gingipains from <i>Porphyromonas gingivalis</i> on the Human Complement System

Katarzyna Popadiak, Jan Potempa, Kristian Riesbeck et al. · The Journal of Immunology · 2007 · 175 citations · Full text

, , +17

Gingival Fluid and Serum in Periodontal Diseases: I. Quantitative Study of Immunoglobulins, Complement Components, and Other Plasma Proteins

Harvey A. Schenkein, Robert J. Genco · Journal of Periodontology · 1977 · 163 citations

, , +17

Interpain A, a Cysteine Proteinase from Prevotella intermedia, Inhibits Complement by Degrading Complement Factor C3

Michal Potempa, Jan Potempa, Tomasz Kantyka et al. · PLoS Pathogens · 2009 · 118 citations · Full text

, , +17

1–5 of 56

Authors

199

  1. JP
    Jan Potempa

    Jagiellonian University, Poland

    9 publications · 896 citations

    9

    h-index

  2. GH
    George Hajishengallis

    University of Pennsylvania, United States

    7 publications · 802 citations

    7

    h-index

  3. AM
    Anna M. Blom

    Lund University, Sweden

    7 publications · 543 citations

    7

    h-index

  4. JD
    John D. Lambris

    University of Pennsylvania, United States

    7 publications · 802 citations

    7

    h-index

  5. HA
    Harvey A. Schenkein

    Virginia Commonwealth University, United States

    6 publications · 407 citations

    6

    h-index

1–5 of 199

Institutions

75

  1. University of Pennsylvania

    Philadelphia, United States

    9 h-index

    43 publications

    4.4K citations

  2. Jagiellonian University

    Krakow, Poland

    7 h-index

    23 publications

    1.8K citations

  3. Lund University

    Lund, Sweden

    7 h-index

    28 publications

    1.7K citations

  4. Virginia Commonwealth University Medical Center

    Richmond, United States

    6 h-index

    25 publications

    1.3K citations

  5. University of Louisville

    Louisville, United States

    6 h-index

    8 publications

    1.1K citations

  6. University at Buffalo, State University of New York

    Buffalo, United States

    6 h-index

    15 publications

    909 citations

  7. Virginia Commonwealth University

    Richmond, United States

    4 h-index

    11 publications

    481 citations

  8. University of Connecticut

    Storrs, United States

    3 h-index

    6 publications

    228 citations

1–8 of 75

Venues

  1. Journal of Periodontal Research

    15 publications · 465 citations

    12

    h-index

  2. The Journal of Immunology

    JI · 6 publications · 593 citations

    6

    h-index

  3. Infection and Immunity

    IAI · 5 publications · 231 citations

    5

    h-index

  4. Journal of Periodontology

    6 publications · 368 citations

    5

    h-index

  5. Journal of Dental Research

    JDR · 4 publications · 174 citations

    4

    h-index

1–5