Concepedia

Complement Evolution

Complement Evolution is a theoretical framework within comparative immunology that elucidates the phylogenetic development and functional diversification of the complement system across species, distinguishing itself by integrating molecular, structural, and pathway-level adaptations to reveal evolutionary pressures shaping innate immune mechanisms.

118

Publications

8.7K

Citations

437

Authors

185

Institutions

Publications per year

2017–2026

10

Parents

Publications

118

Recent advances on the complement system of teleost fish

Hani Boshra, Jun Li, J. Oriol Sunyer · Fish & Shellfish Immunology · 2005 · 674 citations

, , +13

The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor

Lawrence Shapiro, Philipp E. Scherer · Current Biology · 1998 · 656 citations · Full text

, , +12

Structures of complement component C3 provide insights into the function and evolution of immunity

B.J.C. Janssen, Eric G. Huizinga, H.C.A. Raaijmakers et al. · Nature · 2005 · 548 citations · Full text

, , +12

Human complement component C3: cDNA coding sequence and derived primary structure.

M H de Bruijn, G H Fey · Proceedings of the National Academy of Sciences · 1985 · 412 citations · Full text

, , +15

Characterization of C-reactive protein and the complement subcomponent C1t as homologous proteins displaying cyclic pentameric symmetry (pentraxins).

Alexander P. Osmand, Bernard Friedenson, H Gewurz et al. · Proceedings of the National Academy of Sciences · 1977 · 375 citations · Full text

, , +11

1–5 of 118

Authors

437

  1. MN
    Masaru Nonaka

    The University of Tokyo, Japan

    15 publications · 800 citations

    13

    h-index

  2. MM
    Misao Matsushita

    Tokai University, Japan

    6 publications · 590 citations

    6

    h-index

  3. MI
    Mayumi I. Nonaka

    The University of Tokyo, Japan

    6 publications · 225 citations

    6

    h-index

  4. TF
    Teizo Fujita

    Fukushima Medical University, Japan

    5 publications · 372 citations

    5

    h-index

  5. AW
    Alister W. Dodds

    University of Oxford, United Kingdom

    4 publications · 174 citations

    4

    h-index

1–5 of 437

Institutions

185

  1. The University of Tokyo

    Tokyo, Japan

    10 h-index

    19 publications

    818 citations

  2. University of Oxford

    Oxford, United Kingdom

    8 h-index

    13 publications

    1K citations

  3. Tokyo University of Science

    Tokyo, Japan

    6 h-index

    10 publications

    565 citations

  4. University of Pennsylvania

    Philadelphia, United States

    5 h-index

    14 publications

    2.9K citations

  5. Shiga University of Medical Science

    Ōtsu, Japan

    4 h-index

    9 publications

    267 citations

  6. Fukushima Medical University

    Fukushima, Japan

    4 h-index

    15 publications

    1.7K citations

  7. University of Patras

    Pátrai, Greece

    4 h-index

    9 publications

    244 citations

  8. National Institutes of Health

    Bethesda, United States

    4 h-index

    4 publications

    572 citations

1–8 of 185

Venues

  1. The Journal of Immunology

    JI · 14 publications · 895 citations

    14

    h-index

  2. Developmental & Comparative Immunology

    8 publications · 252 citations

    8

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 1.4K citations

    7

    h-index

  4. Fish & Shellfish Immunology

    6 publications · 773 citations

    6

    h-index

  5. Immunogenetics

    5 publications · 350 citations

    5

    h-index

1–5