Concepedia

Complement Activation In Uveitis

Complement Activation in Uveitis is a pathophysiological mechanism within uveal immunology that involves the localized induction of the complement cascade in ocular tissues, distinguishing it by its role in mediating inflammatory damage characteristic of uveitic conditions.

28

Publications

1K

Citations

127

Authors

36

Institutions

Publications per year

2017–2026

2

Parents

Publications

28

Chronic low level complement activation within the eye is controlled by intraocular complement regulatory proteins.

Jeong-Hyeon Sohn, Henry J. Kaplan, Hye-Jung Suk et al. · PubMed · 2000 · 142 citations

, , +17

Proctor Lecture. Experimental autoimmune uveitis: mechanisms of disease and clinical therapeutic indications.

Robert B. Nussenblatt · PubMed · 1991 · 119 citations

, , +16

The Complement System Plays a Critical Role in the Development of Experimental Autoimmune Anterior Uveitis

Purushottam Jha, Jeong-Hyeon Sohn, Qin Xu et al. · Investigative Ophthalmology & Visual Science · 2006 · 72 citations · Full text

, , +17

Genetic deficiency of C3 as well as CNS-targeted expression of the complement inhibitor sCrry ameliorates experimental autoimmune uveoretinitis

Russell W. Read, Alexander J. Szalai, S. D. Vogt et al. · Experimental Eye Research · 2005 · 64 citations

, , +17

IL-1 and TNF receptor-deficient mice show decreased inflammation in an immune complex model of uveitis.

Beatriz E. Brito, Leslie M. O’Rourke, Yuzhen Pan et al. · PubMed · 1999 · 54 citations

, , +17

1–5 of 28

Authors

127

  1. NS
    Nalini S. Bora

    University of Arkansas for Medical Sciences, United States

    6 publications · 319 citations

    5

    h-index

  2. PS
    Puran S. Bora

    University of Arkansas for Medical Sciences, United States

    5 publications · 300 citations

    5

    h-index

  3. PJ
    Purushottam Jha

    University of Arkansas for Medical Sciences, United States

    4 publications · 158 citations

    4

    h-index

  4. HJ
    Henry J. Kaplan

    University of Louisville, United States

    3 publications · 266 citations

    3

    h-index

  5. BM
    Balasubramanian Manickam

    Pfizer (United States), United States

    3 publications · 106 citations

    3

    h-index

1–5 of 127

Institutions

36

  1. University of Arkansas for Medical Sciences

    Little Rock, United States

    4 h-index

    20 publications

    761 citations

  2. University of Louisville

    Louisville, United States

    3 h-index

    9 publications

    565 citations

  3. National Eye Institute

    Bethesda, United States

    2 h-index

    10 publications

    389 citations

  4. University of Catania

    Catania, Italy

    1 h-index

    3 publications

    99 citations

  5. Johns Hopkins University

    Baltimore, United States

    1 h-index

    1 publications

    16 citations

  6. University of Connecticut

    Storrs, United States

    1 h-index

    1 publications

    49 citations

  7. The Affiliated Yongchuan Hospital of Chongqing Medical University

    Chongqing, China

    1 h-index

    8 publications

    120 citations

  8. First Affiliated Hospital of Harbin Medical University

    Harbin, China

    1 h-index

    1 publications

    16 citations

1–8 of 36

Venues

  1. PubMed

    Repository · 8 publications · 430 citations

    8

    h-index

  2. Archives of Ophthalmology

    3 publications · 85 citations

    3

    h-index

  3. Investigative Ophthalmology & Visual Science

    IOVS · 2 publications · 87 citations

    2

    h-index

  4. British Journal of Ophthalmology

    BJO · 2 publications · 31 citations

    2

    h-index

  5. The Journal of Immunology

    JI · 1 publications · 52 citations

    1

    h-index

1–5