Concepedia

Combination Therapy Modeling

Combination Therapy Modeling is a computational or mathematical framework within drug response modeling that characterizes the synergistic, additive, or antagonistic interactions of multiple therapeutic agents administered concurrently to predict overall treatment efficacy and optimize dosing regimens.

68

Publications

2.9K

Citations

274

Authors

146

Institutions

Publications per year

2017–2026

30

Parents

Publications

68

Systems biology and combination therapy in the quest for clinical efficacy

Jonathan B. Fitzgerald, Birgit Schoeberl, Ulrik B. Nielsen et al. · Nature Chemical Biology · 2006 · 583 citations

, , +16

Interaction Index and Different Methods for Determining Drug Interaction in Combination Therapy

Maiying Kong, G. D. Ayers, Reuben Lotan · Journal of Biopharmaceutical Statistics · 2007 · 138 citations

, , +13

Quantitative Models of Phage-Antibiotic Combination Therapy

Rogelio A. Rodriguez-Gonzalez, Chung Yin Leung, Benjamin K. Chan et al. · mSystems · 2020 · 112 citations · Full text

, , +17

Modeling of tumor growth and anticancer effects of combination therapy

Gilbert Koch, Antje‐Christine Walz, Gëzim Lahu et al. · Journal of Pharmacokinetics and Pharmacodynamics · 2009 · 111 citations

, , +16

A general pharmacodynamic interaction model identifies perpetrators and victims in drug interactions

Sebastian G. Wicha, Chunli Chen, Oskar Clewe et al. · Nature Communications · 2017 · 108 citations · Full text

, , +17

1–5 of 68

Authors

274

  1. AF
    Avner Friedman

    The Ohio State University, United States

    3 publications · 144 citations

    3

    h-index

  2. UL
    Urszula Ledzewicz

    Southern Illinois University Edwardsville, United States

    2 publications · 46 citations

    2

    h-index

  3. CW
    Carter Wh

    Virginia Commonwealth University Medical Center, United States

    2 publications · 49 citations

    2

    h-index

  4. HS
    Heinz Schättler

    Washington University in St. Louis, United States

    2 publications · 46 citations

    2

    h-index

  5. PM
    Pavel Mozgunov

    Lancaster University, United Kingdom

    2 publications · 32 citations

    2

    h-index

1–5 of 274

Institutions

146

  1. Harvard University

    Cambridge, United States

    5 h-index

    4 publications

    652 citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    2 h-index

    4 publications

    316 citations

  3. University of Virginia

    Charlottesville, United States

    2 h-index

    7 publications

    143 citations

  4. The Ohio State University

    Columbus, United States

    2 h-index

    3 publications

    181 citations

  5. Renmin University of China

    Beijing, China

    2 h-index

    2 publications

    73 citations

  6. Center for Systems Biology

    Boston, United States

    2 h-index

    2 publications

    599 citations

  7. University of California, Los Angeles

    Los Angeles, United States

    2 h-index

    8 publications

    156 citations

  8. Queensland University of Technology

    Brisbane, Australia

    2 h-index

    8 publications

    214 citations

1–8 of 146

Venues

  1. Scientific Reports

    5 publications · 270 citations

    5

    h-index

  2. Statistics in Medicine

    5 publications · 131 citations

    5

    h-index

  3. PubMed

    Repository · 4 publications · 104 citations

    4

    h-index

  4. Journal of Theoretical Biology

    3 publications · 114 citations

    3

    h-index

  5. PLoS Computational Biology

    2 publications · 31 citations

    2

    h-index

1–5