Concepedia

Combination Therapy Effects

Combination Therapy Effects is a pharmacodynamic construct that characterizes the interplay and resultant biological outcomes—such as synergy, additivity, or antagonism—arising from the concurrent administration of two or more anticancer drugs, distinguishing it from the effects of monotherapies by its focus on drug-drug interactions within therapeutic regimens.

249

Publications

11.9K

Citations

1.5K

Authors

518

Institutions

Publications per year

2017–2026

68

Parents

Publications

249

Recent progress of chemodynamic therapy-induced combination cancer therapy

Xianwen Wang, Xianyan Zhong, Zhuang Liu et al. · Nano Today · 2020 · 706 citations

, , +14

Combination Cancer Therapy Can Confer Benefit via Patient-to-Patient Variability without Drug Additivity or Synergy

Adam C. Palmer, Peter K. Sorger · Cell · 2017 · 666 citations · Full text

, , +13

Combination anti–CTLA-4 plus anti–PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies

Spencer C. Wei, Nana-Ama A.S. Anang, Roshan Sharma et al. · Proceedings of the National Academy of Sciences · 2019 · 361 citations · Full text

, , +17

Synergy, additivism and antagonism in immunosuppression. A critical review.

M. C. Berenbaum · PubMed · 1977 · 337 citations

, , +12

Factors predictive of response, disease progression, and overall survival after dabrafenib and trametinib combination treatment: a pooled analysis of individual patient data from randomised trials

Georgina V. Long, Jean‐Jacques Grob, Paul Nathan et al. · The Lancet Oncology · 2016 · 312 citations

, , +16

1–5 of 249

Authors

1.5K

  1. JC
    Jeong‐Dan Cha

    Jeonbuk National University, South Korea

    4 publications · 327 citations

    4

    h-index

  2. FK
    Fumihiko Kanzawa

    National Cancer Research Institute, United Kingdom

    3 publications · 63 citations

    3

    h-index

  3. SG
    Steven Grant

    Virginia Commonwealth University, United States

    3 publications · 145 citations

    3

    h-index

  4. AC
    Adam C. Palmer

    Harvard University, United States

    2 publications · 723 citations

    2

    h-index

  5. KH
    Kosei Hirakawa

    Osaka City University, Japan

    2 publications · 68 citations

    2

    h-index

1–5 of 1.5K

Institutions

518

  1. German Cancer Research Center

    Heidelberg, Germany

    5 h-index

    16 publications

    1.1K citations

  2. Harvard University

    Cambridge, United States

    4 h-index

    8 publications

    2.6K citations

  3. Amsterdam UMC Location Vrije Universiteit Amsterdam

    Amsterdam, The Netherlands

    4 h-index

    18 publications

    1K citations

  4. Jeonbuk National University

    Jeonju, South Korea

    4 h-index

    8 publications

    358 citations

  5. Heidelberg University

    Heidelberg, Germany

    4 h-index

    11 publications

    841 citations

  6. Massachusetts General Hospital

    Boston, United States

    4 h-index

    4 publications

    451 citations

  7. Stanford University

    Stanford, United States

    3 h-index

    8 publications

    418 citations

  8. Sun Yat-sen University

    Guangzhou, China

    3 h-index

    6 publications

    160 citations

1–8 of 518

Venues

  1. PubMed

    Repository · 28 publications · 1.1K citations

    17

    h-index

  2. Cancer Chemotherapy and Pharmacology

    4 publications · 83 citations

    4

    h-index

  3. Cancer Biology & Therapy

    4 publications · 156 citations

    4

    h-index

  4. Journal of Clinical Oncology

    3 publications · 119 citations

    3

    h-index

  5. Japanese Journal of Cancer Research

    3 publications · 43 citations

    3

    h-index

1–5