Concepedia

Combat Normalization

ComBat Normalization is a statistical harmonization method that corrects batch effects in high-throughput genomic data by adjusting for non-biological variations across batches while preserving biological signals through an empirical Bayes framework.

8

Publications

619

Citations

34

Authors

20

Institutions

Publications per year

2017–2026

6

Variants

Combat

Parents

Publications

8

Correcting for batch effects in case-control microbiome studies

Sean M. Gibbons, Claire Duvallet, Eric J. Alm · PLoS Computational Biology · 2018 · 181 citations · Full text

, , +16

pyComBat, a Python tool for batch effects correction in high-throughput molecular data using empirical Bayes methods

Abdelkader Behdenna, Maximilien Colange, Julien Haziza et al. · BMC Bioinformatics · 2023 · 148 citations · Full text

, , +10

Simulating ComBat: how batch correction can lead to the systematic introduction of false positive results in DNA methylation microarray studies

Tristan Zindler, Helge Frieling, Alexandra Neyazi et al. · BMC Bioinformatics · 2020 · 98 citations · Full text

, , +14

Batch correction of microarray data substantially improves the identification of genes differentially expressed in Rheumatoid Arthritis and Osteoarthritis

Peter Kupfer, Reinhard Guthke, Dirk Pohlers et al. · BMC Medical Genomics · 2012 · 83 citations · Full text

, , +17

pyComBat, a Python tool for batch effects correction in high-throughput molecular data using empirical Bayes methods

Abdelkader Behdenna, Maximilien Colange, Julien Haziza et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 47 citations · Full text

, , +10

1–5 of 8

Authors

34

  1. CA
    Chloé‐Agathe Azencott

    Institut Curie, France

    2 publications · 195 citations

    2

    h-index

  2. CD
    Claire Duvallet

    Massachusetts Institute of Technology, United States

    2 publications · 197 citations

    2

    h-index

  3. AP
    Aryo Pradipta Gema

    University of Edinburgh, United Kingdom

    2 publications · 195 citations

    2

    h-index

  4. AN
    Akpéli Nordor

    Institut Curie, France

    2 publications · 195 citations

    2

    h-index

  5. AB
    Abdelkader Behdenna

    MRC University of Glasgow Centre for Virus Research, United Kingdom

    2 publications · 195 citations

    2

    h-index

1–5 of 34

Institutions

20

  1. Université Paris Sciences et Lettres

    Paris, France

    2 h-index

    2 publications

    195 citations

  2. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    6 publications

    591 citations

  3. University of Edinburgh

    Edinburgh, United Kingdom

    2 h-index

    3 publications

    218 citations

  4. ParisTech

    Paris, France

    2 h-index

    2 publications

    195 citations

  5. Institut Curie

    Paris, France

    2 h-index

    2 publications

    195 citations

  6. Epigénétique et Destin Cellulaire

    Paris, France

    2 h-index

    9 publications

    1K citations

  7. Inserm

    Paris, France

    2 h-index

    2 publications

    195 citations

  8. Broad Institute

    Cambridge, United States

    2 h-index

    4 publications

    394 citations

1–8 of 20

Venues

  1. BMC Bioinformatics

    3 publications · 257 citations

    3

    h-index

  2. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 2 publications · 63 citations

    2

    h-index

  3. BMC Genomics

    1 publications · 35 citations

    1

    h-index

  4. PLoS Computational Biology

    1 publications · 181 citations

    1

    h-index

  5. BMC Medical Genomics

    1 publications · 83 citations

    1

    h-index

1–5