Concepedia

Coiled-coil Dimerization

Coiled-Coil Dimerization is a structural motif in protein quaternary organization where two alpha-helical polypeptide chains wrap around each other in a supercoil, stabilized by characteristic heptad repeats with hydrophobic interactions at the interface, thereby mediating specific and stable protein-protein association.

461

Publications

29.7K

Citations

2.3K

Authors

632

Institutions

Publications per year

2017–2026

83

Parents

Publications

461

MultiCoil: A program for predicting two‐and three‐stranded coiled coils

Ethan Wolf, Peter S. Kim, Bonnie Berger · Protein Science · 1997 · 721 citations

, , +13

Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products

Marjon van Slegtenhorst · Human Molecular Genetics · 1998 · 573 citations · Full text

, , +13

A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins.

John R. McWhirter, Debora L. Galasso, J Y Wang · Molecular and Cellular Biology · 1993 · 417 citations · Full text

, , +14

Synthesis and Functional Analyses of Nuclear Clusterin, a Cell Death Protein

Konstantin Leskov, Dmitry Klokov, Jing Li et al. · Journal of Biological Chemistry · 2003 · 403 citations · Full text

, , +17

Trimerization of a yeast transcriptional activator via a coiled-coil motif

Peter K. Sorger, Hillary C.M. Nelson · Cell · 1989 · 400 citations

, , +14

1–5 of 461

Authors

2.3K

  1. DN
    Derek N. Woolfson

    University of Bristol, United Kingdom

    7 publications · 230 citations

    7

    h-index

  2. RJ
    Roman Jerala

    National Institute of Chemistry, Slovenia

    7 publications · 322 citations

    7

    h-index

  3. RS
    Robert S. Hodges

    University of Alberta, Canada

    7 publications · 379 citations

    7

    h-index

  4. TA
    Tom Alber

    University of California, Berkeley, United States

    5 publications · 619 citations

    5

    h-index

  5. SH
    Samuel H. Gellman

    University of Wisconsin–Madison, United States

    5 publications · 180 citations

    5

    h-index

1–5 of 2.3K

Institutions

632

  1. Harvard University

    Cambridge, United States

    16 h-index

    71 publications

    5.5K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    14 h-index

    35 publications

    5.1K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    62 publications

    3.2K citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    10 h-index

    26 publications

    2.4K citations

  5. University of California, Berkeley

    Berkeley, United States

    9 h-index

    44 publications

    5.6K citations

  6. University of Utah

    Salt Lake City, United States

    9 h-index

    41 publications

    2.9K citations

  7. The University of Tokyo

    Tokyo, Japan

    9 h-index

    43 publications

    2.2K citations

  8. University of Virginia

    Charlottesville, United States

    9 h-index

    35 publications

    3.5K citations

1–8 of 632

Venues

  1. Journal of Biological Chemistry

    JBC · 67 publications · 4.1K citations

    39

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  2. Proceedings of the National Academy of Sciences

    PNAS · 32 publications · 3.3K citations

    28

    h-index

  3. Biochemistry

    31 publications · 1.6K citations

    22

    h-index

  4. Journal of Molecular Biology

    JMB · 20 publications · 1.2K citations

    18

    h-index

  5. Molecular and Cellular Biology

    MCB · 16 publications · 2.3K citations

    16

    h-index

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